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首页> 外文期刊>Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association >Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure
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Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure

机译:血浆Galectin-9水平与药物性急性肝衰竭患者生存率的关系

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BACKGROUND & AIMS: Fewer than 50% of patients with acute liver failure (ALF) recover spontaneously, and ALF has high mortality without liver transplantation. Kupffer cells have been reported to mediate liver inflammation during drug-induced injury. Galectin-9 is produced by Kupffer cells and has diverse roles in regulating immunity. We investigated whether plasma levels of galectin-9 are associated with outcomes of patients with ALF.
机译:背景与目的:仅有不到50%的急性肝衰竭(ALF)患者可以自发康复,并且ALF无需肝移植即可具有很高的死亡率。据报道,枯否细胞在药物诱导的损伤过程中介导肝脏炎症。 Galectin-9由Kupffer细胞产生,在调节免疫力方面具有多种作用。我们调查了galectin-9的血浆水平是否与ALF患者的预后相关。

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