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首页> 外文期刊>Journal of Macromolecular Science. Pure and Applied Chemistry >Suberic acid acts as a dissolving agent as well as a crosslinker for natural polymers (carbohydrate and Protein): A detailed discussion on the chemistry behind the interaction
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Suberic acid acts as a dissolving agent as well as a crosslinker for natural polymers (carbohydrate and Protein): A detailed discussion on the chemistry behind the interaction

机译：辛二酸充当天然聚合物（碳水化合物和蛋白质）的溶解剂和交联剂：关于相互作用背后化学的详细讨论

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摘要

The natural polysaccharide chitosan and the natural protein collagen are widely used for the preparation of biopolymer materials in the presence of suitable crosslinkers. In this study, crosslinking feasibility of a dicarboxylic acid, namely suberic acid was tested using chitosan and collagen and in addition, thermal and mechanical properties were also tested for the resulting biopolymers. A 3D scaffold biopolymer material was prepared using chitosan at 1.0% (w/v) in the presence of suberic acid at 0.2% (w/v), similarly collagen 0.5% (w/v) in the presence of suberic acid 0.2% (w/v). Upon interaction, both the biopolymers displayed appreciable mechanical and thermal properties which add value to the biopolymers for biomedical applications. Molecular docking studies suggests the non-covalent interactions between the natural polymers and suberic acid is the reason behind the improved properties.
机译：在合适的交联剂存在下，天然多糖壳聚糖和天然蛋白胶原蛋白被广泛用于制备生物聚合物材料。在这项研究中，使用壳聚糖和胶原蛋白测试了二羧酸，即辛二酸的交联可行性，此外，还测试了所得生物聚合物的热和机械性能。使用1.0％（w / v）的壳聚糖在0.2％（w / v）的辛二酸存在下，类似地在0.2％的辛二酸（0.5％）（w / v）的胶原蛋白下制备3D支架生物聚合物材料。 w / v）。在相互作用时，两种生物聚合物均显示出明显的机械和热性能，这为生物医学应用的生物聚合物增加了价值。分子对接研究表明，天然聚合物和辛二酸之间的非共价相互作用是改善性能的原因。

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