• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Medical Virology >Amino acid substitutions in the VP7 protein of human rotavirus G3 isolated in China, Russia, Thailand, and Vietnam during 2001-2004.
【24h】

Amino acid substitutions in the VP7 protein of human rotavirus G3 isolated in China, Russia, Thailand, and Vietnam during 2001-2004.

机译：2001年至2004年在中国，俄罗斯，泰国和越南分离出的人类轮状病毒G3 VP7蛋白中的氨基酸取代。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The distribution of rotavirus G-types in the world appears to be changing, especially with the emergence of G3 and G9 in many countries. Sequence analysis of the VP7 gene was performed on the 27 human G3 rotavirus strains isolated in China, Russia, Thailand, and Vietnam during 2001-2004. All the strains studied were clustered into the same branch of the phylogenetic tree. The comparison of the G3 deduced amino acid sequences between the studied Chinese strains and the strains circulating in China during 1986-1992 showed a wide range of amino acid substitutions (up to 13 amino acids in the VP7 antigenic regions). The two considerable changes both from aspartic acid to asparagine were located at positions 96 in antigenic region A and 213 in antigenic region C. Those amino acid substitutions of the Chinese G3 strains might involve in the emergence of G3 rotavirus in China during 2001-2003.
机译：轮状病毒G型的分布在世界范围内似乎正在发生变化，尤其是在许多国家出现了G3和G9时。在2001-2004年期间，对在中国，俄罗斯，泰国和越南分离出的27种人G3轮状病毒株进行了VP7基因的序列分析。所有研究的菌株都聚集在系统发育树的同一分支中。在研究的中国菌株与1986-1992年间在中国流通的菌株之间G3推导的氨基酸序列的比较显示了广泛的氨基酸取代（VP7抗原区最多有13个氨基酸）。从天冬氨酸到天冬酰胺的两个显着变化分别位于抗原区A的96位和抗原区C的213位。中国G3株的那些氨基酸替代可能与2001-2003年间中国G3轮状病毒的出现有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号