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首页> 外文期刊>Journal of Medicinal Chemistry >Analog-Based Drug Discovery.Edited by Janos Fischer and C.Robin Ganellin.Wiley/VCH Verlag GmbH,Weinheim,Germany.
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Analog-Based Drug Discovery.Edited by Janos Fischer and C.Robin Ganellin.Wiley/VCH Verlag GmbH,Weinheim,Germany.

机译：基于类似物的药物发现，由Janos Fischer和C.Robin Ganellin编辑。Wiley/ VCH Verlag GmbH，德国魏因海姆。

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摘要

The demand for effective pharmaceuticals to address unmet medical needs is as great as it ever has been,but with ever-increasing requirements for safety,efficacy,and economy,the difficulties are even greater.Whether new to the field or experienced,drug designers-medicinal chemists-must improve the quality of their designed analogues if they are to shorten the long odds of success.This book modestly states an aim to"describe selected analogue classes in a more detailed manner",but it is actually much more.It is an excellent tutorial on the most important precepts of drug design,and the breadth and generality of the principles described will aid all medicinal chemists.It also serves very well as a reference book,with chapters generously appended with citations.
机译：对于满足未满足的医疗需求的有效药物的需求一直以来都很大，但是随着对安全性，有效性和经济性的要求不断提高，困难甚至更大。无论是新领域还是经验丰富的药物设计师，药用化学家们，如果要缩短设计成功的可能性，就必须提高其设计类似物的质量。这本书谦虚地陈述了“以更详细的方式描述所选类似物类别”的目的，但实际上要更多。关于药物设计最重要的戒律的出色教程，以及所描述原理的广度和通用性将对所有药物化学家有所帮助。它也可以作为参考书，并在章节中大量引用。

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