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首页> 外文期刊>Journal of minimally invasive gynecology >Long-term follow-up after laparoscopic management of endometrial cancer in the obese: a fifteen-year cohort study.
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Long-term follow-up after laparoscopic management of endometrial cancer in the obese: a fifteen-year cohort study.

机译：腹腔镜处理肥胖症子宫内膜癌后的长期随访：一项为期十五年的队列研究。

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STUDY OBJECTIVE: To assess the surgical outcomes and long-term results of laparoscopic treatment of endometrial cancer in obese patients, and compare these results with those of nonobese women. DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Two referral cancer centers. PATIENTS: Fifty-two obese and 155 nonobese women with clinical stage I endometrial cancer managed by laparoscopy from 1990-2005 in two referral centers. INTERVENTIONS: Demographic, surgical, perioperative and pathological characteristics of obese women and nonobese women with endometrial cancer treated by laparoscopy were analyzed and then compared. Recurrence-free and overall survival was calculated by use of Kaplan-Meier method. MEASUREMENTS AND MAIN RESULTS: Median BMI of the study population was 26.2 Kg/m(2). Median BMI among obese patients was 34.2 Kg/m(2). The conversion rate was independent from the BMI of the patient (3.8% vs 4.5%, p = .80). Neither mean operative time (187.5 vs 172 min, p = .11) neither hospital stay (5.2 vs 4.9 days, p = .44) were related with BMI. Lymphadenectomy was considered not feasible in 7 obese (17%) and 8 nonobese (7%) women (p = 0.09). Fewer lymph nodes were retrieved among obese women (8 versus 11, p <.0002). No differences were found between the groups in terms of perioperative complications. Median follow-up was 69 and 71 months for the obese and nonobese, respectively (p = .59). Overall and disease-free 5-year survival rates did not differ between obese and nonobese patients (90.3% and 87.5% versus 88.5% and 89.8%, respectively). CONCLUSION: Despite some limitations, the laparoscopic approach seems to be particularly useful for obese patients with endometrial cancer, with similar survival and recurrence rates and without any more complications compared to the nonobese population.
机译：目的：评估肥胖患者腹腔镜治疗子宫内膜癌的手术效果和长期效果，并将其与非肥胖女性进行比较。设计：回顾性队列研究（加拿大工作组分类II-2）。地点：两个转诊癌症中心。患者：1990年至2005年，在两个转诊中心通过腹腔镜检查管理的52例肥胖和155例非肥胖女性患有I期子宫内膜癌。干预措施：分析并比较了腹腔镜治疗的肥胖妇女和非肥胖子宫内膜癌女性的人口统计学，手术，围手术期和病理学特征。通过使用Kaplan-Meier方法计算无复发生存期和总生存期。测量和主要结果：研究人群的BMI中位数为26.2 Kg / m（2）。肥胖患者的BMI中位数为34.2 Kg / m（2）。转化率与患者的BMI无关（3.8％vs 4.5％，p = .80）。 BMI与平均手术时间（187.5 vs 172 min，p = .11）均无关系，住院时间（5.2 vs 4.9 days，p = .44）均无相关性。 7例肥胖（17％）和8例非肥胖（7％）妇女被认为不行淋巴结清扫术（p = 0.09）。肥胖女性的淋巴结较少（8比11，p <.0002）。两组在围手术期并发症方面没有差异。肥胖和非肥胖的中位随访时间分别为69和71个月（p = 0.59）。肥胖和非肥胖患者的总体和无病5年生存率没有差异（分别为90.3％和87.5％，分别为88.5％和89.8％）。结论：尽管存在一些局限性，但与非肥胖人群相比，腹腔镜手术似乎对肥胖的子宫内膜癌患者特别有用，其存活和复发率相似，且无更多并发症。

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