Expression of authentic substance P receptors in murine and human dendritic cells.

Marriott I; Bost KL

首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Expression of authentic substance P receptors in murine and human dendritic cells.

【24h】

Expression of authentic substance P receptors in murine and human dendritic cells.

机译：真实物质P受体在鼠和人树突状细胞中的表达。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Recent studies from our laboratory have shown that substance P can elicit transcription factor activation in dendritic cells. In the present study, we extend these findings by demonstrating the presence of authentic substance P (NK-1) receptors on both normal murine and human dendritic cells. Specifically, we demonstrate the presence of mRNA encoding NK-1 tachykinin receptors and have utilized specific antibodies to detect the expression of NK-1 receptor protein in dendritic cells by Western blot analysis and flow cytometry. These data provide a crucial first step in determining the potential of substance P to modulate dendritic cell function.

机译：我们实验室的最新研究表明，物质P可以引起树突状细胞中的转录因子激活。在本研究中，我们通过证明正常鼠和人树突状细胞上均存在真实物质P（NK-1）受体来扩展这些发现。具体来说，我们证明了编码NK-1速激肽受体的mRNA的存在，并已利用特异性抗体通过Western blot分析和流式细胞仪检测树突状细胞中NK-1受体蛋白的表达。这些数据为确定物质P调节树突状细胞功能的潜力提供了至关重要的第一步。

著录项

来源
《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |2001年第2期|共11页
作者
Marriott I; Bost KL;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;医学免疫学;
关键词
Dendritic Cells; Receptors; Neurokinin-1; Antigen p150; 95; RNA; Messenger; 树突细胞; 受体; 神经激肽1;

机译：Dendritic Cells;Receptors;Neurokinin-1;Antigen p150;95;RNA;Messenger;树突细胞;受体;神经激肽1;

相似文献

外文文献
中文文献
专利

1. Expression of authentic substance P receptors in murine and human dendritic cells. [J] . Marriott I, Bost KL Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 2001,第1a2期

机译：真实物质P受体在鼠和人树突状细胞中的表达。
2. Identification of delta- and mu-type opioid receptors on human and murine dendritic cells. [J] . Makarenkova VP, Esche C, Kost NV, Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 2001,第1a2期

机译：鉴定人和鼠树突状细胞上的δ型和μ型阿片受体。
3. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. [J] . Muzio M, Bosisio D, Polentarutti N, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2000,第11期

机译：人白细胞中Toll样受体（TLR）的差异表达和调控：树突状细胞中TLR3的选择性表达。
4. Expressions Levels of TGF-betal,FGF2 and their Receptors in Murine Cranial Sutures Analyzed by Keal Time RT-PCR [C] . A.K. GOSAIN, R. SCHAEFE International Society of Craniofacial Surgery . 2005

机译：通过Keal TimeTT-PCR分析的鼠颅缝中TGF-β，FGF2及其受体的表达水平
5. Expression of a Novel Immune Receptor on Lymphoid Tissue Inducer-Derived Cells: A Candidate Murine Homologue Of the Human NKp44 Receptor. [D] . Bui, Viet. 2011

机译：新型免疫受体在淋巴组织诱导物衍生的细胞上的表达：人类NKp44受体的候选小鼠同源物。
6. Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells. [O] . A Morelli, A Larregina, I Chuluyán, 1996

机译：C5a受体（CD88）在皮肤树突状细胞上的表达和调节。 C5a对皮肤迁移树突细胞的趋化作用。
7. Borrelia burgdorferi elicited-IL-10 suppresses the production of inflammatory mediators, phagocytosis, and expression of co-stimulatory receptors by murine macrophages and/or dendritic cells. [O] . Yutein Chung, Nan Zhang, R Mark Wooten 2013

机译：伯氏疏螺旋体引发的IL-10抑制小鼠巨噬细胞和/或树突细胞的炎症介质的产生，吞噬作用和共刺激受体的表达。

Expression of authentic substance P receptors in murine and human dendritic cells.

摘要

著录项

相似文献

相关主题

期刊订阅