Sensory neurons regulate immunoglobulin secretion of spleen cells: cellular analysis of bidirectional communications between neurons and immune cells.

Hikawa N; Takenaka T

首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Sensory neurons regulate immunoglobulin secretion of spleen cells: cellular analysis of bidirectional communications between neurons and immune cells.

【24h】

Sensory neurons regulate immunoglobulin secretion of spleen cells: cellular analysis of bidirectional communications between neurons and immune cells.

机译：感觉神经元调节脾脏细胞免疫球蛋白的分泌：对神经元和免疫细胞之间双向通讯的细胞分析。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The effects of primary sensory neurons in the dorsal root ganglia (DRG) on immunoglobulin (Ig)-secreting activity of spleen cells were investigated in culture. The conditioned medium (CM) of normal spleen cells stimulated DRG neurons to release neurokinin A which increased the number of Ig-secreting spleen cells. In contrast, the CM of concanavalin A-induced suppressor spleen cells induced the release of vasoactive intestinal peptide, an inhibitor of Ig secretion of spleen, from DRG neurons. These findings indicate that sensory neurons can help and suppress Ig secretion, and these bidirectional activities are controlled by the factors released from immune cells.

机译：在培养中研究了背根神经节（DRG）中初级感觉神经元对脾细胞免疫球蛋白（Ig）分泌活性的影响。正常脾细胞的条件培养基（CM）刺激DRG神经元释放神经激肽A，从而增加分泌Ig的脾细胞的数量。相反，伴刀豆球蛋白A诱导的抑制性脾细胞的CM诱导DRG神经元释放血管活性肠肽，该肽是脾Ig分泌的抑制剂。这些发现表明感觉神经元可以帮助和抑制Ig分泌，并且这些双向活动受免疫细胞释放的因子的控制。

著录项

来源
《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |1996年第2期|共8页
作者
Hikawa N; Takenaka T;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Ganglia; Spinal; Immunoglobulins; Spleen; Neuropeptides; Vasoactive Intestinal Peptide; 神经节; 脊; 免疫球蛋白类; 脾;

机译：Ganglia;Spinal;Immunoglobulins;Spleen;Neuropeptides;Vasoactive Intestinal Peptide;神经节;脊;免疫球蛋白类;脾;

相似文献

外文文献
中文文献
专利

1. Sensory neurons regulate immunoglobulin secretion of spleen cells: cellular analysis of bidirectional communications between neurons and immune cells. [J] . Hikawa N, Takenaka T Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 1996,第2期

机译：感觉神经元调节脾脏细胞免疫球蛋白的分泌：对神经元和免疫细胞之间双向通讯的细胞分析。
2. Neuron-specific Hu proteins sub-cellular localization in primary sensory neurons. [J] . Fornaro M, Raimondo S, Lee JM, Annals of anatomy =: Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft . 2007,第3期

机译：神经元特异性Hu蛋白在主要感觉神经元中的亚细胞定位。
3. Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system [J] . Kodama Daisuke, Hirai Takao, Kondo Hisataka, FEBS letters. . 2017,第3期

机译：体外共培养系统中感觉神经元和成骨细胞之间的双向通信
4. ssi-integrin Cytoskeleton Signaling Regulates Sensory Neurons Response to Matrix Dimensionality [C] . Andrcia Ribeiro, D. Hughes, S. Vargo, Annual meeting of the Society for Biomaterials . 2011

机译：ssi整合素细胞骨架信号调节感觉神经元对矩阵维数的响应。
5. The effect of adoptive transfer of spleen cells on MPTP induced changes in microglia and dopamine neuron loss. [D] . Bhatt, Mansi Amit. 2012

机译：脾细胞过继转移对MPTP的影响引起小胶质细胞的改变和多巴胺神经元的损失。
6. Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons [O] . Ali H. Shaib, Angelina Staudt, Ali Harb, 2018

机译：钙依赖性激活蛋白分泌的旁系同源物差异性调节感觉神经元的突触传递和肽分泌。
7. Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells. [O] . Alexandra Anderson, Henry Laurenson-Schafer, Frederick A Partridge, 2013

机译：5-羟色胺能化学感应神经元通过调节上皮细胞中的G蛋白信号传导来改变秀丽隐杆线虫的免疫应答。

Sensory neurons regulate immunoglobulin secretion of spleen cells: cellular analysis of bidirectional communications between neurons and immune cells.

摘要

著录项

相似文献

相关主题

期刊订阅