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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Autoantibodies involved in neuropsychiatric manifestations associated with systemic lupus erythematosus.
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Autoantibodies involved in neuropsychiatric manifestations associated with systemic lupus erythematosus.

机译：自身抗体涉及与系统性红斑狼疮有关的神经精神病学表现。

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摘要

In the course of Systemic Lupus Erythematosus (SLE), a variety of neuropsychiatric disturbances is reported with a prevalence ranging from 17% to 75%. The diagnosis of these syndromes is difficult and requires a careful psychiatric evaluation. Distinct autoantibodies detectable in serum or cerebrospinal fluid of patients with SLE are associated with the presence of neuropsychiatric disorders. These autoantibodies may have a pathogenic relevance in neuropsychiatric SLE or they may be merely an epiphenomenon. This review describes the various autoantibodies reported to be associated with neuropsychiatric manifestations in SLE and discusses their possible role.
机译：据报道，在系统性红斑狼疮（SLE）的过程中，各种神经精神障碍的发生率在17％至75％之间。这些综合征的诊断很困难，需要仔细的精神病学评估。 SLE患者血清或脑脊液中可检测到的不同自身抗体与神经精神疾病的存在有关。这些自身抗体可能与神经精神病性SLE具有致病相关性，或者它们可能只是表象。这篇综述描述了据报道与SLE中神经精神病学表现有关的各种自身抗体，并讨论了它们的可能作用。

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