Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants

YukiN.; HirataK.

首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants

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Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants

机译：Fisher综合征及其变体中抗GQ1b抗体的补体激活

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IgG anti-GQ1b antibodies are associated with Fisher syndrome (FS) as well as with its more and less extensive variants, Bickerstaff brainstem encephalitis and acute ophthalmoparesis. Passive transfer experiments provide evidence that anti-ganglioside antibodies and complement are pathogenic in the development of FS. In the current in vitro study, we could not demonstrate the association of complement activation with disease extension.

机译：IgG抗GQ1b抗体与Fisher综合征（FS）以及其越来越多的变体，比克斯塔夫脑干脑炎和急性眼瘫有关。被动转移实验提供了证据，证明神经节苷脂抗体和补体在FS的发展中具有致病性。在当前的体外研究中，我们无法证明补体激活与疾病扩展之间的关联。

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《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |2013年第2期|共2页
作者
YukiN.; HirataK.;
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正文语种 eng
中图分类神经病学;
关键词
Anti-GQ1b antibody; Bickerstaff brainstem encephalitis; Complement; Fisher syndrome;

机译：抗GQ1b抗体;比格斯塔夫脑干脑炎;补体;费雪综合征;

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1. Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants [J] . YukiN., HirataK. Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 2013,第1a2期

机译：Fisher综合征及其变体中抗GQ1b抗体的补体激活
2. Bickerstaff brainstem encephalitis and Fisher syndrome: Anti-GQ1b antibody syndrome [J] . ShahrizailaN., YukiN. Journal of Neurology, Neurosurgery and Psychiatry . 2013,第5期

机译：Bickersaff脑干脑炎和Fisher综合征：抗GQ1B抗体综合征
3. Fisher syndrome or Bickerstaff brainstem encephalitis? Anti-GQ1b IgG antibody syndrome involving both the peripheral and central nervous systems. [J] . Ogawara K, Kuwabara S, Yuki N Muscle and Nerve . 2002,第6期

机译：Fisher综合征还是Bickerstaff脑干脑炎？抗GQ1b IgG抗体综合症涉及周围和中枢神经系统。
4. Bioluminescence activated by antibody-enzyme fragment complementation following target engagement [C] . Andrew S Dixon, Brett K Baumgartner, Sylvia Krippner, World biomaterials congress . 2016

机译：靶标结合后抗体-酶片段互补激活生物发光
5. A novel approach to control and regulate the classical complement pathway: Highly specific inhibition of C1q globular head binding to human IgG using an engineered single chain antibody variable fragment; recruiting C1q to HER2 /neu positive cells using truncated bispecific antibodies [D] . Hwang, Hee Young 2007

机译：一种控制和调节经典补体途径的新方法：使用工程化的单链抗体可变片段高度特异性地抑制C1q球头与人IgG的结合；使用截短的双特异性抗体将C1q募集到HER2 / neu阳性细胞
6. Guillain-Barré Syndrome- and Miller Fisher Syndrome-Associated Campylobacter jejuni Lipopolysaccharides Induce Anti-GM1 and Anti-GQ1b Antibodies in Rabbits [O] . C. W. Ang, M. A. De Klerk, H. P. Endtz, 2001

机译：Guillain-Barré综合征和Miller Fisher综合征相关的空肠弯曲杆菌脂多糖诱导兔抗GM1和抗GQ1b抗体
7. Bickerstaff brainstem encephalitis and Fisher syndrome: anti-GQ1b antibody syndrome [O] . N. Shahrizaila, N. Yuki 2012

机译：Bickersaff脑干脑炎和Fisher综合征：抗GQ1B抗体综合征
8. Complement Activation in Rats by Liposomes and Liposome-Encapsulated Hemoglobin:Evidence for Anti-Lipid Antibodies and Alternative Pathway Activation [R] . Szebeni, J., Wassef, N. M., Spielberg, H., 1994

机译：脂质体和脂质体包裹的血红蛋白对大鼠的补体激活：抗脂质抗体和替代途径激活的证据

Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants

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