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首页> 外文期刊>Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres >Preparation of magnetic and pH-responsive chitosan microcapsules via sonochemical method
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Preparation of magnetic and pH-responsive chitosan microcapsules via sonochemical method

机译:声化学法制备磁性和pH响应型壳聚糖微胶囊

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摘要

Magnetic and pH-responsive chitosan microcapsules (MPRCMCs) were prepared by a simple sonochemical method. Superparamagnetic oleic acid modified Fe3O4 nanoparticles (OA-Fe3O4 NPs) and hydrophobic drugs could be directly loaded into MPRCMCs during sonication. The obtained microcapsules had a well-defined spherical morphology with the average size of 2 mu m. The microcapsules showed an excellent magnetic property. In addition, the pH-responsive controlled release of coumarin 6 (C6) from MPRCMCs indicated that the developed microcapsules could be a promising candidate for drugs carriers.
机译:磁性和pH响应的壳聚糖微胶囊(MPRCMC)通过简单的声化学方法制备。在超声处理过程中,超顺磁性油酸修饰的Fe3O4纳米颗粒(OA-Fe3O4 NPs)和疏水性药物可以直接加载到MPRCMC中。所获得的微胶囊具有明确的球形形态,平均尺寸为2μm。微胶囊显示出优异的磁性。此外,从MPRCMCs中释放出香豆素6(C6)的pH响应控制释放表明,开发的微胶囊可能是药物载体的有希望的候选者。

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