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首页> 外文期刊>Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres >Photostabilization of sunscreen oil through preparation of a free-flowing powder
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Photostabilization of sunscreen oil through preparation of a free-flowing powder

机译：通过制备自由流动的粉末来稳定防晒油

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摘要

Octyl-p-methoxycinnamate (OMC) is a sun-blocking agent that absorbs ultraviolet (UV) radiation in UVB range. However, when exposed to sunlight, OMC is converted into a less UV-absorbent form, which reduces its effectiveness. The aim of this study was to stabilize the oil by microencapsulation and to convert it into a free-flowing powder form. In addition, the study aimed to develop a suitable high-performance liquid chromatography method to detect the oil in the presence of its degradation product. OMC was microencapsulated by the congealable disperse-phase encapsulation using carnauba wax (cw) and beeswax (bw) at different wax-to-drug ratios (2:1 and 4:1). The photostability of the oil was investigated by exposing the microspheres to UV radiation. After 180min of exposure, the photoprotective abilities of all the tested formulae were similar and reached about 82%. However, physicochemical assessment showed superiority of cw microspheres over their bw analogues.
机译：对甲氧基肉桂酸辛酯（OMC）是一种吸收UVB范围内的紫外线（UV）的防晒剂。但是，当暴露在阳光下时，OMC会转变为吸收较少紫外线的形式，从而降低其有效性。这项研究的目的是通过微囊化稳定油并将其转化为自由流动的粉末形式。此外，该研究旨在开发一种合适的高效液相色谱方法，以检测油中降解产物的存在。使用巴西棕榈蜡（cw）和蜂蜡（bw）以不同的蜡药比（2：1和4：1）通过可凝结的分散相包封将OMC微囊化。通过将微球暴露于紫外线辐射下研究了油的光稳定性。暴露180分钟后，所有测试配方的光防护能力均相似，达到约82％。然而，理化评估显示连续血微球优于其连续血球类似物。

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