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首页> 外文期刊>Journal of nephrology. >Low protein diets and outcome of renal patients.
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Low protein diets and outcome of renal patients.

机译:低蛋白饮食和肾病患者的预后。

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Protein-restricted diets have been proposed in patients with chronic renal failure (CRF) to correct uremic symptoms and to slow the progression of CRF thus delaying the initiation of dialysis. Questions have been raised about the compliance to such diets, their nutritional safety and efficacy. In two-thirds of selected and motivated patients, satisfactory compliance is observed; however, in the overall predialysis population, compliance is fair and does not exceed 50%. When patients are carefully monitored, protein-restricted diets, rather than inducing malnutrition, may prevent it. Moreover, the outcome of these patients, when treated by dialysis, is not affected by prior dietary prescription. A small but real beneficial effect of low protein diet (LPD) on the rate of progression of CRF is observed in nondiabetic renal diseases, but their beneficial effect seems to be greater in diabetic renal disease. Meta-analyses confirm that LPD can effectively postpone renal replacement therapy by moderately slowing the decline in GFR and also by substantially delaying the onset of uremic symptoms.
机译:对于慢性肾功能衰竭(CRF)的患者,已经提出了蛋白质限制饮食,以纠正尿毒症症状并减慢CRF的进程,从而延迟透析的开始。人们对这些饮食的依从性,营养安全性和功效提出了疑问。在三分之二的积极进取患者中,观察到满意的依从性;但是,在整个透析前人群中,依从性是公平的,并且不超过50%。当对患者进行仔细监测时,限制蛋白质饮食而不是引起营养不良可以预防这种情况。而且,通过透析治疗这些患者的结局不受先前饮食处方的影响。在非糖尿病性肾脏疾病中观察到低蛋白饮食(LPD)对CRF进展速度的微小但真正的有益作用,但在糖尿病性肾脏疾病中它们的有益作用似乎更大。荟萃分析证实,LPD可通过适度减慢GFR的下降并显着延迟尿毒症症状的发作来有效地推迟肾脏替代治疗。

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