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首页> 外文期刊>Journal of nuclear cardiology: official publication of the American Society of Nuclear Cardiology >Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras.
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Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras.

机译：用于快速心肌灌注成像的新型固态探测器专用心脏照相机：与标准双探测器照相机的多中心比较。

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OBJECTIVE: To compare the diagnostic performance of a new dedicated ultrafast solid-state cardiac camera (Discovery NM 530c [DNM]) with standard dual detector cameras (S-SPECT) in myocardial perfusion imaging. The primary goal was a per-patient analysis of diagnostic performance of the DNM using S-SPECT as the reference standard. METHODS AND RESULTS: In total, 168 patients underwent one-day Tc-99m tetrofosmin rest/stress myocardial perfusion SPECT. DNM and S-SPECT images were obtained with the same injected doses. The DNM camera uses an array of cadmium zinc telluride pixilated detectors and a multipinhole collimator simultaneously imaging all cardiac views with no moving parts. Rest and stress acquisition times were 4 and 2 minutes for DNM and 14 and 12 minutes for S-SPECT. Two blinded readers independently interpreted all scans on a patient level and on a vascular territory level using a standard five-point scale. Interobserver differences were resolved by a third observer. Agreement between DNM and S-SPECT for presence or absence of myocardial perfusion defects on a per-patient analysis was 91.9% and 92.5%, respectively. Correlation coefficients of rest and stress left ventricular ejection fractions were 0.87 (P < .01) and 0.90 (P < .01). CONCLUSION: The diagnostic performance of DNM is comparable to that of S-SPECT on a per-patient basis. However, superior image quality can be achieved with significantly shorter acquisition times with DNM because of improved count sensitivity and image contrast over S-SPECT.
机译：目的：比较新型专用超快固态心脏照相机（Discovery NM 530c [DNM]）与标准双探测器照相机（S-SPECT）在心肌灌注成像中的诊断性能。主要目标是使用S-SPECT作为参考标准对DNM的诊断性能进行每位患者分析。方法和结果：总共168例患者接受了为期一天的Tc-99m替罗福明静息/应激心肌灌注SPECT治疗。以相同的注射剂量获得DNM和S-SPECT图像。 DNM摄像机使用了一组碲化镉锌像素化检测器和一个多针孔准直仪，可同时对所有心脏视图进行成像，而无需移动部件。 DNM的休息和压力获取时间分别为4和2分钟，S-SPECT为14和12分钟。两名不知情的读者使用标准的五点量表独立解释了患者和血管区域的所有扫描结果。观察员之间的分歧由第三位观察员解决。根据患者分析，DNM和S-SPECT之间存在或不存在心肌灌注缺陷的一致性分别为91.9％和92.5％。静息与左心室射血分数的相关系数分别为0.87（P <.01）和0.90（P <.01）。结论：在每位患者的基础上，DNM的诊断性能与S-SPECT相当。但是，由于与S-SPECT相比具有更高的计数灵敏度和图像对比度，因此使用DNM可以显着缩短采集时间，从而获得卓越的图像质量。

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