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首页> 外文期刊>Journal of Neurophysiology >Errors of memory-guided saccades in humans with lesions of the frontal eye field and the dorsolateral prefrontal cortex.
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Errors of memory-guided saccades in humans with lesions of the frontal eye field and the dorsolateral prefrontal cortex.

机译:具有额眼视野和背外侧前额叶皮层损害的人类记忆引导扫视的错误。

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摘要

Behavioral studies in monkeys and humans suggest that systematic and variable errors of memory-guided saccades reflect distinct neuronal computations in primate spatial memory. We recorded memory-guided saccades with a 2-s delay in three patients with unilateral ischemic lesions of the frontal eye field and in three patients with unilateral ischemic lesions of the frontal eye field and the dorsolateral prefrontal cortex. Results suggest that systematic errors of memory-guided saccades originate in the frontal eye field and variable errors in the dorsolateral prefrontal cortex. These data are the first human lesion data to support the hypothesis that these regions provide functionally distinct contributions to spatial short-term memory.
机译:猴子和人类的行为研究表明,记忆引导扫视的系统性和可变性错误反映了灵长类动物空间记忆中不同的神经元计算。我们记录了记忆引导扫视的延迟2 s在三名额叶视野单侧缺血性病变的患者和三名额叶视野与背外侧前额叶皮质单侧缺血性病变的患者中。结果表明,记忆引导扫视的系统误差源于额叶视野,而背侧前额叶皮质存在可变误差。这些数据是第一个支持以下假设的人类病变数据:这些区域在功能上为空间短期记忆提供了不同的贡献。

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