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首页> 外文期刊>Journal of Neuroscience Methods >A computer-controlled maze environment for testing visual memory in the rat.
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A computer-controlled maze environment for testing visual memory in the rat.

机译:用于测试大鼠视觉记忆的计算机控制迷宫环境。

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摘要

A computer-controlled version of a Y-maze was developed to allow automated testing of rats' learning and memory with visual stimuli. Each of the 3 arms terminated with 2 adjacent monochromatic screens, 43 cm from the maze centre, providing a total stimulus area 47 cm wide by 18.5 cm high. The displays were abstract patterns extending across 2 screens, generated by algorithms which provided a large pool of discriminable patterns. The patterns used were of 2 general classes: Scenes (internally complex patterns with varying numbers of foreground shapes distributed across contrasted backgrounds) and Objects (internally homogeneous single figures, confined to the central part of the display). They could be stationary or have oscillatory movement. Subjects' location in the maze was monitored by infrared beam photodetectors; approach to correct patterns was rewarded with food. Pigmented rats of the Hooded Lister and Dark Agouti strains were tested. All could acquire 2-pair concurrent visual discriminations comprising 2 positive and 2 negative patterns, either Scenes or Objects; most could acquire 4-pair discriminations. Dark Agouti rats generally performed better than Hooded Listers. A novel training procedure using one positive and many negative patterns resulted in rapid learning of novel discriminations with either moving or non-moving patterns. The apparatus is an effective environment for visual learning by rats, suitable for a wide range of tasks in neuropsychology and psychopharmacology.
机译:开发了计算机控制的Y迷宫版本,可以通过视觉刺激自动测试大鼠的学习和记忆能力。 3个臂中的每一个都以2个相邻的单色屏幕终止,距离迷宫中心43厘米,提供了47厘米(宽)×18.5厘米(高)的总刺激区域。这些显示是跨越2个屏幕的抽象图案,这些图案是由算法生成的,该算法提供了大量可识别的图案。所使用的模式分为2类:场景(内部复杂的模式,在对比的背景中分布有数量不等的前景形状)和对象(内部同质的单个图形,仅限于显示的中央部分)。它们可能是静止的,也可能是振荡的。受试者在迷宫中的位置由红外光束光电探测器监控;纠正模式的方法得到了食物的奖励。测试了Hooded Lister和Dark Agouti品系的色素大鼠。所有人都能获得2对并发的视觉辨别力,包括场景或物体的2种正面和2种负面模式;大多数人会获得四对歧视。深色Agouti大鼠通常比Hooded Listers表现更好。一种使用一个积极和许多消极模式的新颖训练程序,可以快速学习具有移动或不移动模式的新颖歧视。该设备是大鼠进行视觉学习的有效环境,适用于神经心理学和心理药理学的各种任务。

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