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首页> 外文期刊>Journal of Neuroscience Methods >A simple analytical method for determining the steady-state potential in models of geometrically complex neurons.
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A simple analytical method for determining the steady-state potential in models of geometrically complex neurons.

机译:确定几何复杂神经元模型中稳态电位的简单分析方法。

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摘要

A method is presented for solving the cable equation for a spiking neuron below firing threshold or a nonspiking neuron of arbitrary geometry under constant stimulation. The neuron structure is considered as a tree composed of a set of cylinder cables of three types (terminal, intermediate and branching) characterized by their lengths, diameters and linear membrane properties. The stimulation can result from either a uniform conductance-change over a whole cable segment or a point injection of a current. Other special segments are considered (synapses, voltage clamp, lumped soma). Equations are given for replacing any segment with its Thevenin equivalent, i.e. resistance and electromotive force. The step by step use of these elementary equations allows one to find the Thevenin equivalent of the whole neuron and to determine the steady-state membrane potential at any point.
机译:提出了一种方法,用于求解在持续刺激下激发阈值以下的尖峰神经元或任意几何形状的非尖峰神经元的电缆方程。神经元结构被认为是由一组圆柱电缆组成的树,该圆柱电缆以其长度,直径和线性膜特性为特征,具有三种类型(末端,中间和分支)。刺激可能是由于整个电缆段上的均匀电导变化或电流的点注入引起的。考虑其他特殊部分(突触,电压钳,集总体)。给出了用戴维宁当量(即电阻和电动势)代替任何段的方程。这些基本方程式的逐步使用使人们可以找到整个神经元的戴维宁当量,并可以在任何点确定稳态膜电位。

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