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首页> 外文期刊>Journal of Neuroscience Methods >An improved method for protecting and fixing the lumbar catheters placed in the spinal subarachnoid space of rats.
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An improved method for protecting and fixing the lumbar catheters placed in the spinal subarachnoid space of rats.

机译：一种改进的保护和固定放置在大鼠脊髓蛛网膜下腔中的腰导管的方法。

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摘要

The chronic intrathecal catheterization of the subarachnoid space in the rat is a very useful model in the research of neuroscience, anesthesiology, neurotoxicity, and etc. To avoid high postoperative mortality and neurological impairment, the catheterization from the lumbar interspace has been widely used in recent years. But one of the most discouraging disadvantages is that the external portion of the chronic indwelling catheters is easily damaged by rats. Besides, the short length of catheter left in the subarachnoid space in addition to its slimness makes it difficult for proper fixation. To improve the abovementioned situations, we designed a protector to protect the external portion of the catheters and developed a simple method for better fixation. Results suggest that this is an excellent method for protecting and fixing the lumbar catheters placed in the subarachnoid space of rats, and this method did not affect the sensory and motor function of the rat. The general conditions of the rats were unswayed.
机译：大鼠蛛网膜下腔的慢性鞘内导管插入术在神经科学，麻醉学，神经毒性等研究中是非常有用的模型。为避免术后高死亡率和神经系统损伤，近来从腰间隙插入导管已被广泛使用年份。但是，最令人沮丧的缺点之一是，慢性留置导管的外部很容易被老鼠损坏。此外，除了纤细外，留在蛛网膜下腔中的导管短，难以正确固定。为了改善上述情况，我们设计了一种保护器来保护导管的外部，并开发了一种用于更好固定的简单方法。结果表明，这是保护和固定放置在大鼠蛛网膜下腔中的腰导管的一种极好的方法，该方法并未影响大鼠的感觉和运动功能。大鼠的一般情况保持不变。

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