首页> 外文期刊>Journal of Neuroscience Methods >Detecting and tracking tremor in spike trains using the rectangular model based extended Kalman smoother.
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Detecting and tracking tremor in spike trains using the rectangular model based extended Kalman smoother.

机译:使用基于矩形模型的扩展卡尔曼平滑器来检测和跟踪峰值列车中的震颤。

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摘要

Tremor is one of the most disabling symptoms in patients with movement disorders such as Parkinson's disease (PD) and essential tremor (ET). Spike trains extracted from microelectrode recordings are used to study the relationship of tremor exhibited by neuronal signals to physical tremor as measured with electromyograms (EMG), gyroscopes, or accelerometers. We describe a new method for continuously tracking the instantaneous tremor frequency and amplitude in spike trains based on a new state-space model and the extended Kalman smoother. This method can be used to detect periods of statistically significant tremor in recordings with intermittent tremor.
机译:震颤是患有运动障碍(如帕金森氏病(PD)和原发性震颤(ET))的患者中最致残的症状之一。从微电极记录中提取的尖峰序列用于研究神经元信号所表现出的震颤与物理震颤的关系,用肌电图(EMG),陀螺仪或加速度计进行测量。我们描述了一种基于新的状态空间模型和扩展的卡尔曼平滑器来连续跟踪峰值列车中瞬时震颤频率和振幅的新方法。此方法可用于检测间歇性震颤记录中具有统计意义的震颤周期。

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