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Bisection of biotinylated soft spherical structures.

机译:生物素化的软球形结构两等分。

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摘要

Biotin, a water soluble vitamin, upon conjugation with ditryptophan methyl ester affords soft spherical structures in the nanometer to micrometer range. The evolution of such morphology is ascribed to favorable interaction between biotin and tryptophan residues as suggested for high affinity biotin-avidin interaction. We report unprecedented observation that biotinylated soft spherical structures undergo bisection to reveal hemispherical capsule-like structures, in the presence of avidin. This study suggests singular approach of tuning bioinspired morphologies via natural principles of interaction and affinity. We envisage that such hemispherical capsules provide an expeditious entry into interesting soft structures which may be harnessed for potential applications.
机译:生物素,一种水溶性维生素,与二色氨酸甲酯结合后,可提供纳米级至微米级的柔软球形结构。如对于高亲和力生物素-亲和素相互作用所建议的,这种形态的演变归因于生物素和色氨酸残基之间的有利相互作用。我们报告了前所未有的观察,在亲和素存在下,生物素化的软球形结构经过两部分以揭示半球形的胶囊状结构。这项研究提出了一种通过相互作用和亲和力的自然原理来调节生物启发形态的奇异方法。我们设想,这样的半球形胶囊可以迅速进入有趣的软结构,可以利用这些软结构进行潜在的应用。

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