All data on both vaccines must be considered

Pim Kon

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All data on both vaccines must be considered

机译：必须考虑两种疫苗的所有数据

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The government chose the human papillomavirus (HPV) vaccine of GlaxoSmithKline (GSK), Cervarix, after considering protection against cancer causing HPV 16 and 18, HPV 6 and 11 (which cause genital warts), and HPV strains not included in the vaccine formulation; price; and supply. Its decision was based on a comprehensive review of published and unpublished clinical efficacy and safety data. New data from GSK included the demonstration of high protection against HPV 16 and 18 for over 6.4 years, the longest protection reported for any cervical cancer vaccine to date. The study is being extended for up to 9.5 years in a subset of women.

机译：政府考虑保护免受引起HPV 16和18，HPV 6和11（引起生殖器疣）的癌症以及未包含在疫苗制剂中的HPV菌株后，选择了Cervarix的葛兰素史克（GSK）人乳头瘤病毒（HPV）疫苗;价钱;和供应。它的决定基于对已发表和未发表的临床疗效和安全性数据的全面审查。 GSK的新数据包括对HPV 16和18的高度保护已被证明超过6.4年，这是迄今为止所有宫颈癌疫苗报道的最长保护时间。这项研究在一部分女性中被延长了长达9.5年。

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《Journal of nursing and healthcare of chronic illness》 |2010年第4期|共1页
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Pim Kon;
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中图分类护理学;
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1. All data on both vaccines must be considered [J] . Pim Kon Journal of nursing and healthcare of chronic illness . 2010,第4期

机译：必须考虑两种疫苗的所有数据
2. Should Sex Be Considered an Effect Modifier in the Evaluation of Influenza Vaccine Effectiveness? [J] . Catharine Chambers, Danuta M Skowronski, Caren Rose, Open Forum Infectious Diseases . 2018,第9期

机译：在评估流感疫苗效果时，应考虑将性别作为一种效果调节剂吗？
3. Author's reply to: Could cross-immunological reactivity to Trypanosoma cruzi antigens be considered a rational strategy for designing vaccines against cancer? [J] . Osinaga Eduardo, Freire Teresa, Ubillos Luis International Journal of Cancer =: Journal International du Cancer . 2016,第9期

机译：作者的回复：对克鲁斯锥虫抗原的交叉免疫反应是否可以被认为是设计抗癌疫苗的合理策略？
4. A rating system that open-data repositories must satisfy to be considered OER: Reusing open data resources in teaching [C] . Nelson Piedra, Janneth Chicaiza, Jorge López, IEEE Global Engineering Education Conference . 2017

机译：必须满足开放数据存储库的评级系统才能被考虑为OER：在教学中重用开放数据资源
5. Improving global monitoring of vaccine safety: An evaluation of the World Health Organization Programme for International Drug Monitoring and Adverse Reactions Database on how they serve the needs of vaccine safety. [D] . Letourneau, Megan A. 2007

机译：改进疫苗安全性的全球监测：对世界卫生组织国际药物监测和不良反应数据库计划的评估，说明它们如何满足疫苗安全性需求。
6. Double–blind control of the data manager doesnt have any impact on data entry reliability and should be considered as an avoidable cost [O] . Davide Mauri, Vasiliki Karampoiki, Jacopo Mauri, 2008

机译：数据管理器的双盲控制不会对数据输入的可靠性产生任何影响应将其视为可避免的成本
7. The thermodynamic changes that occur upon mixing five models of formamide and three models of water, including the miscibility of these model combinations itself, is studied by performing Monte Carlo computer simulations using an appropriately chosen thermodynamic cycle and the method of thermodynamic integration. The results show that the mixing of these two components is close to the ideal mixing, as both the energy and entropy of mixing turn out to be rather close to the ideal term in the entire composition range. Concerning the energy of mixing, the OPLS/AA-mod model of formamide behaves in a qualitatively different way than the other models considered. Thus, this model results in negative, while the other ones in positive energy of mixing values in combination with all three water models considered. Experimental data supports this latter behavior. Although the Helmholtz free energy of mixing always turns out to be negative in the entire composition range, the majority of the model combinations tested either show limited miscibility, or, at least, approach the miscibility limit very closely in certain compositions. Concerning both the miscibility and the energy of mixing of these model combinations, we recommend the use of the combination of the CHARMM formamide and TIP4P water models in simulations of water-formamide mixtures. [O] . Kiss, Bálint, Fábián, Balázs, Idrissi, Abdenacer, 2017

机译：通过使用适当选择的热力学循环和热力学积分方法进行蒙特卡罗计算机模拟，研究了将五种甲酰胺模型和三种水模型混合在一起时发生的热力学变化，包括这些模型组合本身的可混溶性。结果表明这两种组分的混合接近于理想的混合，因为混合的能量和熵在整个组成范围内都非常接近理想的项。关于混合的能量，甲酰胺的OPLS / AA-mod模型与其他模型相比，在质量上有不同的表现。因此，该模型得出的结果是负的，而其他模型则综合考虑了所有三个水模型的结果的正能量。实验数据支持后一种行为。尽管混合的亥姆霍兹自由能在整个组成范围内始终为负，但大多数测试模型组合显示出有限的混溶性，或至少非常接近某些组合物的混溶性极限。关于这些模型组合的可混溶性和混合能量，我们建议在水-甲酰胺混合物的模拟中使用CHARMM甲酰胺和TIP4P水模型的组合。
8. Should Cultivated Exoerythrocytic Parasites be Considered as a Source of Antigen for a Malaria Vaccine. [R] . Beaudoin, R. L. 1977

机译：应将栽培的红细胞外寄生虫视为疟疾疫苗的抗原来源。

All data on both vaccines must be considered

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