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Changes in gut toll-like receptor-4 and nod-like receptor family pyrin domain containing-3 innate pathways in liver cirrhosis rats with bacterial translocation

机译:细菌性肝硬化大鼠肠内toll样受体4和nod样受体家族含3个蛋白的内源性途径的改变

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摘要

Background: Bacterial translocation (BT) plays a vital role in the development of liver cirrhosis (LC); however, little is known regarding the role of gut innate immunity in cirrhosis. Aims: To observe the influence of BT on multiple vital organs in LC and changes in the gut toll-like receptor-4 and nod-like receptor family pyrin domain containing-3 innate pathways in liver cirrhosis rats with bacterial translocation.
机译:背景:细菌易位(BT)在肝硬化(LC)的发展中起着至关重要的作用。然而,关于肠道固有免疫在肝硬化中的作用知之甚少。目的:观察BT对肝硬化大鼠细菌性易位的LC的多个重要器官的影响以及肠道toll样受体4和nod样受体家族含3个固有结构的内源性途径的变化。

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