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首页> 外文期刊>Journal of paediatrics and child health >Early identification of autism: A comparison of the checklist for autism in toddlers and the modified checklist for autism in toddlers
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Early identification of autism: A comparison of the checklist for autism in toddlers and the modified checklist for autism in toddlers

机译：自闭症的早期识别：幼儿自闭症检查表与改良后的幼儿自闭症检查表的比较

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There is still debate as to what is the most effective strategy for identifying the early signs of autism in very young children. Two levels of screening having been advocated: broad-based developmental surveillance and targeted screening. Two popular tools for use in developmental surveillance are the Checklist for Autism in Toddlers (CHAT) and the Modified Checklist for Autism in Toddlers (M-CHAT). The purpose of this article is to summarise the current evidence for screening for autistic symptoms in very young children using CHAT and M-CHAT. A systematic search was carried out of electronic database and other sources for original studies which evaluated the use of CHAT and M-CHAT in screening for autism in children younger than 5 years of age. Studies were included for review if they evaluated the sensitivity and/or specificity of CHAT or M-CHAT, or described the best age to administer these instruments. The available evidence suggests that characteristic behaviours in autism should be evident in simple forms before the age of 18 months, while screening at 24 months should be conducted to identify those who regress. Administering a screening tool during 18- to 24-month well-child visits improves early identification of autism, while the stability of diagnosis at the ages of 18 months and 24 months is confirmed. M-CHAT has slightly better sensitivity and specificity compared to CHAT, and is preferable to use as a developmental surveillance screening instrument.
机译：关于识别幼儿中自闭症早期迹象的最有效策略仍存在争议。提倡两种筛选：基础广泛的发育监测和靶向筛选。用于发育监测的两种流行工具是“幼儿自闭症检查表”（CHAT）和“幼儿自闭症检查表”（M-CHAT）。本文的目的是总结使用CHAT和M-CHAT筛查年幼儿童自闭症症状的最新证据。我们对电子数据库和其他来源进行了系统搜索，以寻找原始研究，评估了CHAT和M-CHAT在筛查5岁以下儿童自闭症中的用途。如果研究评估了CHAT或M-CHAT的敏感性和/或特异性，或描述了使用这些仪器的最佳年龄，则将其纳入研究范围。现有证据表明，自闭症的特征性行为应在18个月大之前以简单的形式表现出来，而在24个月时应进行筛查以识别出那些自闭症患者。在18到24个月的儿童探访期间使用筛查工具可以改善自闭症的早期识别能力，同时可以确定18个月和24个月年龄的诊断的稳定性。与CHAT相比，M-CHAT的敏感性和特异性略强，因此更适合用作发育监测筛选工具。

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