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首页> 外文期刊>Journal of pain and symptom management. >Episodic (breakthrough) pain prevalence in a population of cancer pain patients. comparison of clinical diagnoses with the qudei - Italian questionnaire for intense episodic pain
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Episodic (breakthrough) pain prevalence in a population of cancer pain patients. comparison of clinical diagnoses with the qudei - Italian questionnaire for intense episodic pain

机译:癌症疼痛患者人群中的发作性(突破性)疼痛患病率。 qudei-Italian问卷对剧烈发作性疼痛的临床诊断比较

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摘要

Context: Breakthrough/episodic pain (BP-EP) diagnosis is often based on clinical experience, and different opinions exist, even among palliative care clinicians, about its definition and application to clinical practice. Objectives: The primary aim of this study was to assess the prevalence and clinical characteristics of BP-EP in an unselected Italian population of patients with cancer-related chronic pain, based on clinical diagnosis and on the use of an assessment tool, the Questionnaire for Intense Episodic Pain (QUDEI). Methods: A cross-sectional multicenter prevalence study of 240 consecutive cancer pain patients was carried out. The physicians participating in the study attended a training session aimed at defining and recognizing BP-EP. The QUDEI, a screening and assessment tool based on patient interview, diagnosed the presence of BP-EP in patients regularly taking analgesics for the previous three days and who had at least one pain flare in the previous 24 hours. Clinical evaluation and questionnaire application were carried out by different health care providers. Results: The estimated prevalence of BP-EP was 73% (95% confidence interval [CI] = 67%, 79%) when the diagnosis was made by physicians and 66% (95% CI = 60%, 72%) when the QUDEI was applied (86% agreement). When only patients with baseline pain less than or equal to six were included in the analysis, the above prevalences decreased to 67% and 60%, respectively. Conclusion: Because BP-EP is a significant phenomenon in cancer pain management, its appropriate recognition requires a more widely, internationally accepted general definition and specific validated tools for its screening and evaluation.
机译:背景:突破性/发作性疼痛(BP-EP)诊断通常基于临床经验,就姑息治疗临床医生而言,其定义和在临床实践中的使用也存在不同的观点。目的:本研究的主要目的是根据临床诊断和评估工具(问卷调查表)评估未选择的意大利癌症相关慢性疼痛患者的BP-EP患病率和临床特征。剧烈发作性疼痛(QUDEI)。方法:对240名连续的癌症疼痛患者进行横断面多中心患病率研究。参与研究的医生参加了旨在定义和识别BP-EP的培训课程。 QUDEI是一种基于患者访谈的筛查和评估工具,诊断出前三天定期服用镇痛药且在前24小时内至少有一次疼痛发作的患者中存在BP-EP。临床评估和问卷调查由不同的卫生保健提供者进行。结果:医生诊断出的BP-EP患病率估计为73%(95%置信区间[CI] = 67%,79%),而当诊断为BP-EP时,估计患病率为66%(95%CI = 60%,72%)。 QUDEI被应用(86%同意)。当仅基线疼痛小于或等于6的患者纳入分析时,上述患病率分别降至67%和60%。结论:由于BP-EP在癌症疼痛治疗中是一种重要现象,因此对其进行适当的识别需要更广泛,国际上公认的一般定义和经过验证的特定工具进行筛查和评估。

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