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Web-based physiotherapy for people moderately affected with Multiple Sclerosis; Quantitative and qualitative data from a randomized, controlled pilot study

机译:基于网络的物理疗法,适合中度多发性硬化症患者;来自随机对照试验研究的定量和定性数据

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Objective: To explore the effectiveness and participant experience of web-based physiotherapy for people moderately affected with Multiple Sclerosis (MS) and to provide data to establish the sample size required for a fully powered, definitive randomized controlled study. Design: A randomized controlled pilot study. Setting: Rehabilitation centre and participants' homes. Subjects: Thirty community dwelling adults moderately affected by MS (Expanded Disability Status Scale 5-6.5). Interventions: Twelve weeks of individualised web-based physiotherapy completed twice per week or usual care (control). Online exercise diaries were monitored; participants were telephoned weekly by the physiotherapist and exercise programmes altered remotely by the physiotherapist as required. Main measures: The following outcomes were completed at baseline and after 12 weeks; 25 Foot Walk, Berg Balance Scale, Timed Up and Go, Multiple Sclerosis Impact Scale, Leeds MS Quality of Life Scale, MS-Related Symptom Checklist and Hospital Anxiety and Depression Scale. The intervention group also completed a website evaluation questionnaire and interviews. Results: Participants reported that website was easy to use, convenient, and motivating and would be happy to use in the future. There was no statistically significant difference in the primary outcome measure, the timed 25ft walk in the intervention group (P=0.170), or other secondary outcome measures, except the Multiple Sclerosis Impact Scale (P=0.048). Effect sizes were generally small to moderate. Conclusion: People with MS were very positive about web-based physiotherapy. The results suggested that 80 participants, 40 in each group, would be sufficient for a fully powered, definitive randomized controlled trial.
机译:目的:探讨基于网络的物理疗法对中度多发性硬化症(MS)患者的疗效和参与者经验,并提供数据以建立完全有力,确定性随机对照研究所需的样本量。设计:一项随机对照试验研究。地点:康复中心和参与者的家。受试者:30名受MS影响中等程度的社区居民(扩展的残疾状况量表5-6.5)。干预措施:十二周的基于网络的个性化理疗每周完成两次或进行常规护理(对照)。监测在线运动日记;物理治疗师每周都会给参与者打电话,物理治疗师会根据需要远程更改锻炼程序。主要措施:在基线时和12周后完成以下结果; 25步行,伯格平衡量表,定时走动,多发性硬化症影响量表,利兹MS生活质量量表,MS相关症状清单和医院焦虑症和抑郁量表。干预小组还完成了网站评估问卷和访谈。结果:参与者报告说该网站易于使用,方便且具有激励性,并且将来会很乐意使用。除了多发性硬化症影响量表(P = 0.048)外,主要结果指标,干预组的定时25英尺步行(P = 0.170)或其他次要结果指标在统计​​学上无显着差异。效果大小通常较小到中等。结论:MS患者对基于网络的物理治疗非常满意。结果表明,有80名参与者(每组40名)足以进行完全有力的确定性随机对照试验。

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