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首页> 外文期刊>Clinics in dermatology >The role of skin substitutes in the treatment of burn injuries.
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The role of skin substitutes in the treatment of burn injuries.

机译：皮肤替代品在烧伤治疗中的作用。

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摘要

Extensive burn wounds are difficult to manage and repair. Several engineered skin substitutes have been developed to aid in this process. These substitutes are designed with particular objectives in mind which dictate the circumstances under which they can, and should, be employed to promote healing or prepare the burn wound for final closure with autograft. This article discusses some of the rationale behind the use of skin substitutes and reviews some of the substitutes in use at the present time. Current perspectives suggest that skin substitute use is still in its infancy and that there is some way to go before their role in clinical practice becomes clear. Nevertheless the prospect of being able to supply new wound repair components and to influence the healing process to modify outcome and improve the quality of the healed burn wound will ensure a continuing high degree of interest in these potentially useful and beneficial medical devices.
机译：大量烧伤难以处理和修复。已经开发了几种工程皮肤替代品来辅助这一过程。设计这些替代品时要考虑到特定的目标，这些目标决定了在何种情况下可以并且应该使用它们来促进愈合或为自体移植的最终闭合做好烧伤创口的准备。本文讨论了使用皮肤替代品背后的一些基本原理，并回顾了当前使用的一些替代品。当前的观点表明，皮肤替代品的使用仍处于起步阶段，在临床实践中它们的作用尚不清楚之前，还有一些路要走。然而，能够提供新的伤口修复组件并影响愈合过程以改变结局并改善愈合的烧伤创面质量的前景将确保对这些潜在有用和有益的医疗器械的持续高度关注。

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