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首页> 外文期刊>Journal of neurology >Acute measles encephalitis in adults.
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Acute measles encephalitis in adults.

机译:成人急性麻疹脑炎。

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摘要

Sirs: Acute measles encephalitis (AME) commonly occurs in children [12], The pathogenetic mechanism has not been fully elucidated. Limited information is available about AME in adults. We report 2 cases of adult AME.Case 1: A 20-year-old woman developed coma 3 days after she had developed a high-grade fever with Koplik spots followed by a rash. Routine blood tests showed evidence of a mild inflammation. The IgG and IgM titers of an-timeasles antibodies were elevated in both the serum (IgG, 1:128; IgM, 1:14.7) and cerebrospinal fluid (IgG, 1:12.8; IgM, 1:14.7). The patient received betamethasone (12 mg/d) and gamma globulin (5 g/d) intravenously from day 6 of the illness. Her level of consciousness gradually improved beginning on day 60. On day 270, she was discharged without residual motor symptoms, although mild psychomotor impairment persisted.
机译:主席先生:急性麻疹脑炎(AME)多见于儿童[12],其致病机制尚未完全阐明。成人有关AME的信息有限。我们报告了2例成人AME。病例1:一名20岁妇女在出现高热并伴有Koplik斑点和皮疹的三天后出现了昏迷。常规血液检查显示有轻度炎症迹象。血清(IgG,1:128; IgM,1:14.7)和脑脊液(IgG,1:12.8; IgM,1:14.7)均提高了抗-天疱疮抗体的IgG和IgM滴度。从患病的第六天开始,患者静脉接受倍他米松(12毫克/天)和丙种球蛋白(5克/天)。从第60天开始,她的意识水平逐渐提高。在第270天,尽管轻度精神运动障碍持续存在,但她出院时没有残余运动症状。

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