Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid.

Noachtar S

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Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid.

机译：与缓慢释放左旋多巴/苄丝肼相比，使用缓慢释放的丙戊酸治疗特发性躁动腿综合征（RLS）。

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We aimed to compare the efficacy of valproic acid (VPA) on paresthesias and sleep in RLS to that of levodopa (LD). Twenty patients with idiopathic restless legs syndrome (RLS) were treated with 600 mg slow-release VPA and 200 mg slow-release LD+50mg benserazid in a randomized, placebo-controlled, cross-over, double-blind setting with polysomography (PSG) at the end of each 3-week treatment periods. There was no major difference between the efficacy of valproic acid or LD. Periodic leg movements in sleep (PLMS) and PLM arousal index (PLMAI) significantly decreased with LD (p

机译：我们旨在比较丙戊酸（VPA）对左旋多巴（LD）的感觉异常和睡眠中RLS的疗效。 20例特发性躁动腿综合征（RLS）患者在随机，安慰剂对照，交叉，双盲和多导睡眠监测（PSG）中接受600 mg缓释VPA和200 mg缓释LD + 50mg苄丝肼治疗在每个3周的治疗期结束时。丙戊酸或LD的疗效之间无重大差异。 LD患者的定期睡眠中腿部运动（PLMS）和PLM唤醒指数（PLMAI）显着降低（p

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《Journal of neurology》 |2004年第5期|共5页
作者
Noachtar S;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Discharge (release); Slow; Valproic Acid; Syndrome; 丙戊酸; 综合征;

机译：Discharge (release);Slow;Valproic Acid;Syndrome;丙戊酸;综合征;

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1. Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid. [J] . Noachtar S Journal of neurology . 2004,第5期

机译：与缓慢释放左旋多巴/苄丝肼相比，使用缓慢释放的丙戊酸治疗特发性躁动腿综合征（RLS）。
2. Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: results from a multi-center, randomized, active controlled trial. [J] . Trenkwalder C, Benes H, Grote L, Movement disorders . 2007,第5期

机译：卡麦角林与左旋多巴相比，用于治疗严重的躁动性腿综合征：来自一项多中心，随机，主动对照试验的结果。
3. Treatment of idiopathic restless legs syndrome (RLS) with the D2-agonist cabergoline--an open clinical trial. [J] . Stiasny K, Robbecke J, Schuler P, Sleep . 2000,第3期

机译：D2激动剂卡麦角林治疗特发性躁动腿综合征（RLS）-一项开放临床试验。
4. Restless legs syndrome (RLS) [C] . Hirata Koichi, Suzuki Keisuke, Miyamoto Tomoyuki, 2011 IEEE/ICME International Conference on Complex Medical Engineering . 2011

机译：不安腿综合症（RLS）
5. The Effectiveness of Aquatic Therapy on Sleep Quality and the Reduction of Restelss Legs Symptoms in an Individual with Restless Legs Syndrome [D] . Jeppson, Scott . 2019

机译：水生治疗对睡眠质量的有效性以及躁动腿综合征的个体中不安腿症状的减少
6. Evaluating daytime alertness in individuals with restless legs syndrome (RLS) compared to sleep restricted controls [O] . Charlene Gamaldo, Amy R. Benbrook, Richard P Allen, -1

机译：与睡眠受限对照相比评估躁动腿综合征（RLS）患者的白天警觉性
7. Treatment of Idiopathic Restless Legs Syndrome (RLS) with the D2-agonist Cabergoline — An Open Clinical Trial [O] . Karin Stiasny, Julia Röbbecke, Peter Schüler, 2000

机译：用D2-激动剂Cabergoline治疗特发性躁不入腿综合征（RLS） - 开放式临床试验

Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid.

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