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首页> 外文期刊>Journal of neurology >Comparison of secondary vascular prevention in practice after cerebral ischemia and coronary heart disease.
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Comparison of secondary vascular prevention in practice after cerebral ischemia and coronary heart disease.

机译：在脑缺血和冠心病后实践中二级血管预防的比较。

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BACKGROUND: Secondary prevention measures in patients with cerebral ischemia or coronary heart disease (CHD) consist of vascular risk factors management and antithrombotic therapy. The aim of this study was to compare how secondary prevention measures are applied in practice between patients with a history of CHD or cerebral ischemia. METHOD: We compared vascular risk factors management and antithrombotic therapy between patients with a history of CHD and patients with a history of cerebral ischemia that occurred 2 months to 6 years earlier. Whether patients were properly treated or not was determined by a comparison between their current treatments and European guidelines for stroke and CHD management. RESULTS: We included 107 consecutive patients with a history of cerebral ischemia and 85 consecutive patients with a history of CHD. We found that: (i) most patients did not receive an appropriate secondary prevention in both groups: 76 of 107 patients with previous cerebral ischemia (71 %) and 73 of 85patients with CHD (85.9 %); (ii) identification of risk factors, such as hypercholesterolemia, diabetes mellitus and smoking, did not differ between both groups, but arterial hypertension was more frequent in CHD patients; (iii) an inappropriate management of risk factors was more frequent in patients with TIA vs. ischemic stroke, and angina pectoris vs. myocardial infarction; (iv) arterial hypertension and hypercholesterolemia were the 2 more frequent risk factors that were not properly treated; (v) more than half diabetic patients had hyperglycemia >/= 126 mg/dl in both groups; (vi) patients with previous CHD had twice more frequently stopped smoking than those with cerebral ischemia. CONCLUSION: Many patients were not properly treated in both groups, and differences between practice and guidelines were more frequent in the CHD group, where guidelines are more strict.
机译：背景：脑缺血或冠心病（CHD）患者的二级预防措施包括血管危险因素管理和抗血栓治疗。这项研究的目的是比较在患有冠心病或脑缺血病史的患者之间，如何在实践中应用二级预防措施。方法：我们比较了有冠心病病史的患者和有脑缺血病史的2个月至6年前发生的血管危险因素管理和抗血栓治疗。通过将他们目前的治疗方法与欧洲中风和冠心病管理指南进行比较，确定患者是否得到适当治疗。结果：我们纳入了107例有脑缺血史的连续患者和85例有冠心病史的连续患者。我们发现：（i）两组的大多数患者均未接受适当的二级预防：107例既往有脑缺血的患者（71％）和85例CHD的患者73（85.9％）; （ii）两组间高胆固醇血症，糖尿病和吸烟等危险因素的识别无差异，但冠心病患者的动脉高血压更为常见; （iii）TIA与缺血性中风，心绞痛与心肌梗死相比，TIA患者对危险因素的管理更为频繁; （iv）动脉高血压和高胆固醇血症是未得到适当治疗的两个较常见的危险因素; （v）两组中一半以上的糖尿病患者高血糖> / = 126 mg / dl; （vi）先前患有冠心病的患者戒烟的频率是脑缺血患者的两倍。结论：两组患者均未得到适当的治疗，冠心病组中实践和指南之间的差异更为频繁，而指南更严格。

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