Voltage-gated potassium channel complex antibodies in Creutzfeldt-Jakob disease

FujitaK.; YuasaT.; WatanabeO.; TakahashiY.; HashiguchiS.; AdachiK.; IzumiY.; KajiR.

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Voltage-gated potassium channel complex antibodies in Creutzfeldt-Jakob disease

机译：电压门控钾通道复合物抗体在克雅氏病中

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Clinical presentations of Creutzfeldt-Jakob disease (CJD) can be mimicked by those of immune-mediated encepha-lopathies, including limbic encephalitis with anti-voltage-gated potassium channel (VGKC) complex antibodies [1, 2]. To date, anti-VGKC complex antibodies have been reported to be negative in CJD [1], thereby regarded as important to differentiate non-CJD dementia from CJD [3]. Here we report a patient with definite CJD who had serum anti-VGKC complex antibodies.

机译：克雅氏病（CJD）的临床表现可通过免疫介导的脑病来模仿，包括带有抗电压门控钾通道（VGKC）复合抗体的边缘性脑炎[1，2]。迄今为止，据报道抗VGKC复合抗体在CJD中呈阴性[1]，因此被认为对区分非CJD痴呆和CJD具有重要意义[3]。在这里，我们报告了一位患有明确CJD的患者，该患者患有血清抗VGKC复合抗体。

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《Journal of neurology》 |2012年第10期|共2页
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FujitaK.; YuasaT.; WatanabeO.; TakahashiY.; HashiguchiS.; AdachiK.; IzumiY.; KajiR.;
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正文语种 eng
中图分类神经病学;
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1. Creutzfeldt-Jakob Disease-Like Periodic Sharp Wave Complexes in Voltage-Gated Potassium Channel-Complex Antibodies Encephalitis: A Case Report [J] . Savard Martin, Irani Sarosh R., Guillemette Annie, Journal of Clinical Neurophysiology . 2016,第1期

机译：电压门控钾通道复杂抗体脑炎的Creutzfeldt-Jakob病样周期性尖波复合物：病例报告
2. Voltage-gated potassium channel complex antibodies in Creutzfeldt-Jakob disease [J] . FujitaK., YuasaT., WatanabeO., Journal of neurology . 2012,第10期

机译：电压门控钾通道复合物抗体在克雅氏病中
3. EEG Differences in Two Clinically Similar Rapid Dementias: Voltage-Gated Potassium Channel Complex-Associated Autoimmune Encephalitis and Creutzfeldt-Jakob Disease [J] . Freund Brin, Probasco John C., Cervenka Mackenzie C., Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) . 2019,第2期

机译：eg差异在两个临床上类似的快速痴呆：电压门控钾通道复杂相关的自身免疫脑炎和Creutzfeldt-jakob疾病
4. A Multiplatform Strategy for the Discovery of Conventional Monoclonal Antibodies That Inhibit the Voltage-Gated Potassium Channel Kvl.3. [C] . Yelena Bisharyan, J. Bednenko, R. Harriman, Protein Engineering Summit. . 2018

机译：一种抑制电压门控钾通道KVL的常规单克隆抗体的多平台策略。
5. Molecular modelling of voltage-gated potassium, sodium and calcium channels complexed with metal ions and small-molecule ligands. [D] . Bruhova, Iva. 2009

机译：与金属离子和小分子配体络合的电压门控钾，钠和钙通道的分子模型。
6. Creutzfeldt-Jakob disease-like periodic sharp wave complexes in voltage-gated potassium channel-complex antibodies encephalitis : A Case Report [O] . Martin Savard, Sarosh R. Irani, Annie Guillemette, -1

机译：电压门控钾通道复合抗体脑炎中的克雅氏病样周期性尖波复合物：一例报告
7. Limbic Encephalitis Associated With Anti–Voltage-Gated Potassium Channel Complex Antibodies Mimicking Creutzfeldt-Jakob Disease [O] . Ji Yeoun Yoo, Lawrence J. Hirsch 2014

机译：与反电压门控钾通道复合抗体相关的肢体脑炎，模仿克雷托茨菲尔特 - 雅各布病

Voltage-gated potassium channel complex antibodies in Creutzfeldt-Jakob disease

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