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首页> 外文期刊>Journal of neurology >Rehabilitation interventions in multiple sclerosis: an overview.
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Rehabilitation interventions in multiple sclerosis: an overview.

机译：多发性硬化症的康复干预：概述。

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Multiple sclerosis is a complex, heterogeneous disease associated with long-term disability. Despite the availability of advanced disease-modifying and symptomatic therapies that may decrease activity and progression of disease and alleviate complaints to a certain extent, there is still a need for comprehensive rehabilitation interventions in order to reduce sequels and symptoms of the disease on personal activities and social participation to achieve the highest possible independence and the best quality of life. Timing and setting of rehabilitation interventions should be selected individually depending on disease phase, functional deficits, personal requirements, as well as specific goals. In addition, limitations and disease-specific characteristics that may influence rehabilitation outcome should be noted. Rehabilitation interventions should be considered early for maintaining functional capacity and reducing risk for losing important abilities or independence. Due to gradual failure of adaptive compensatory mechanisms along the course of disease, benefits of rehabilitation interventions are generally higher in earlier phases of MS. Inpatient and outpatient multidisciplinary rehabilitation has been shown to be beneficial in improving disability, participation and quality of life despite progression of the disease. Good evidence exists for different specific interventions improving physical and cognitive performance. Other important issues responsible for beneficial effects of comprehensive rehabilitation in MS include education, instruction, and information of patients and caregivers. Comprehensive assessment of health domains in MS patients using standardized framework and common language for describing the impact of disease at different levels, using International Classification of Functioning, Disability and Health (ICF) core sets may increase the knowledge of needs of these patients for more efficient and adapted rehabilitation interventions meeting these individual requirements, and promote perception and acceptance of rehabilitation as a valuable treatment option in MS. ICF core sets may increase the knowledge of more efficient and adapted rehabilitation measures meeting more properly individual requirements, and promote perception and acceptance of rehabilitation as a valuable treatment option in MS.
机译：多发性硬化症是与长期残疾相关的复杂的异质性疾病。尽管有先进的疾病缓解和对症治疗方法可以在一定程度上降低疾病的活动和进展并减轻不适，但仍需要全面的康复干预措施，以减少个人活动和疾病的后遗症和症状。社会参与，以实现最高的独立性和最佳的生活质量。应当根据疾病阶段，功能缺陷，个人需求以及具体目标，分别选择康复干预的时间和地点。此外，应注意可能影响康复结果的局限性和疾病特异性。应该尽早考虑康复干预措施，以保持功能能力并减少丧失重要能力或独立性的风险。由于适应性补偿机制在疾病过程中逐渐失效，因此在MS早期阶段，康复干预措施的收益通常更高。尽管疾病进展，住院和门诊多学科康复已被证明在改善残疾，参与和生活质量方面是有益的。对于改善身体和认知表现的各种具体干预措施，有充分的证据。导致MS全面康复的有益作用的其他重要问题包括患者，护理人员的教育，指导和信息。使用国际功能，残疾与健康分类（ICF）核心集，使用标准化框架和通用语言描述疾病在不同级别的影响，全面评估MS患者的健康领域，可能会增加这些患者对更有效治疗的需求的知识并调整适应性干预措施以满足这些个人要求，并促进对康复的认识和接受，将其作为MS中有价值的治疗选择。 ICF核心集可以增加人们对更有效和适应的康复措施的了解，以满足更恰当的个人需求，并促进康复的认识和接受，将其作为MS中有价值的治疗选择。

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