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首页> 外文期刊>Journal of neurology >Ischemic stroke in young adults: classification and risk factors.
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Ischemic stroke in young adults: classification and risk factors.

机译：年轻人缺血性中风：分类和危险因素。

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摘要

Our aim was to analyze an important subgroup represented by young adult patients (19-45?years) with acute ischemic stroke according to stroke classification (including the novel ASCO score), infarct types and risk factors. All patients up to 45?years of age with an acute ischemic stroke confirmed by MRI and treated in our stroke unit from 2006 to 2009 were recruited for this study. Patients were neurologically examined and underwent thorough stroke work-up. One hundred four patients (58 women, 46 men) with a mean age of 38?±?6.9?years were evaluated. The mean NIHSS score (±SD) was 3?±?5 on admission and 1?±?4 on discharge. The classification using TOAST/ASCO (grade 1) was as follows: Macroangiopathic 10.6%/8.7%, cardiac origin 21.2%/10.6%, microangiopathic 9.6%/9.6%, other causes 19.2%/13.5% and undetermined 39.4%/19.2% (for A0S0C0O0). The most common risk factors were smoking (55.2%), hypertension (31.4%) and hyperlipidemia (27.6%). Twenty nine of 74 patients with TEE (39.2%) had a patent foramen ovale (PFO). Hypoplastic posterior circulation (21.9%) and migraine (21.0%) were also quite common. Young adult ischemic stroke patients share many of the characteristic risk factors with the general elderly ischemic stroke population. If regular work-up includes TEE, a high percentage of young patients reveal comorbidities with PFO, hypoplasia of the posterior circulation and migraine. The ASCO classification should be favored for a better classification of coexisting stroke subtypes and lower number of undetermined etiologies in this patient group.
机译：我们的目的是根据中风分类（包括新的ASCO评分），梗塞类型和危险因素，分析由急性缺血性中风的年轻成人患者（19-45岁）代表的重要亚组。本研究招募了2006年至2009年间经MRI确认并在我们的卒中科接受治疗的45岁以下急性缺血性卒中的所有患者。对患者进行了神经系统检查，并对他们进行了全面的中风检查。评估了平均年龄38？±？6.9？岁的104例患者（58名女性，46名男性）。入院时NIHSS平均得分（±SD）为3？±？5，出院时为1？±？4。使用TOAST / ASCO（1级）的分类如下：大血管病10.6％/ 8.7％，心脏起源21.2％/ 10.6％，微血管病9.6％/ 9.6％，其他原因19.2％/ 13.5％，未定39.4％/ 19.2％ （对于A0S0C0O0）。最常见的危险因素是吸烟（55.2％），高血压（31.4％）和高脂血症（27.6％）。 74名TEE患者中有29名（39.2％）患有卵圆孔未闭（PFO）。发育不良的后循环（21.9％）和偏头痛（21.0％）也很常见。年轻的成人缺血性中风患者与一般的老年人缺血性中风人群共享许多特征性危险因素。如果定期检查包括TEE，则高百分比的年轻患者显示合并有PFO，后循环发育不良和偏头痛。应优先考虑ASCO分类，以更好地分类并存此卒中亚型，并减少该病因中病因未明的数量。

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