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首页> 外文期刊>Journal of neurology >Multiple sclerosis in North Norway, and first appearance in an indigenous population.
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Multiple sclerosis in North Norway, and first appearance in an indigenous population.

机译：挪威北部多发性硬化症，首次在土著居民中出现。

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摘要

This study was performed to determine the prevalence of multiple sclerosis (MS) in 1993 and annual incidence rates 1983-1992, and to examine whether the disease occurs among the Sami people. According to earlier reports the two northernmost counties of Norway, Troms and Finnmark with 225,000 inhabitants, have a relatively low prevalence of MS: 20.6 per 100,000 in 1973 and 31.5 in 1983. Also no person who is of pure Sami heritage (i.e., with both parents speaking Sami natively) has been found with the disease. Except for the introduction of magnetic resonance imaging as a diagnostic tool, there has been no significant change in the neurological service in the area during the past 20 years. Files of patients with the diagnosis of MS were reviewed, and questionnaires were sent to all patients alive on the prevalence day of 1 January 1993. The prevalence in 1993 was 73.0 per 100,000. The mean crude annual incidence rate was 3.5 per 100,000 during the period 1983-1992 compared with 3.0 during 1974-1982. In 1983 there were no pure Sami among the MS patients, but one had a Sami father. On 1 January 1993 there were three patients with both Sami parents and three with only one Sami parent, which is a rate that is still lower than would be expected if the prevalence of MS among the Sami were similar to that in the rest of the Norwegian population. The study shows that the incidence of MS in Troms and Finnmark has been increasing over the past 10 years, but is still lower than on the western coast and in the eastern part of Norway. The lowest incidence is found in Finnmark, where the Sami population is highest. During the past 10 years MS has also been diagnosed among the Sami population.
机译：这项研究的目的是确定1993年多发性硬化症（MS）的患病率以及1983-1992年的年发病率，并检查该疾病是否在萨米人中发生。根据较早的报道，挪威最北端的两个县特罗姆斯和芬马克拥有225,000居民，其MS患病率相对较低：1973年为每10万人中有20.6人，1983年为31.5。已发现患有这种疾病的父母）。除了引入磁共振成像作为诊断工具外，在过去的20年中，该地区的神经科服务没有发生重大变化。回顾了诊断为MS的患者的档案，并在1993年1月1日患病率当天向所有活着的患者发送了问卷。1993年的患病率为每100000例73.​​0。 1983-1992年期间，原油的平均年发病率为3.5 / 10万，而1974-1982年为3.0。 1983年，MS患者中没有纯萨米人，但其中一位父亲是萨米人。在1993年1月1日，三名病人都是萨米人父母，三人只有一名萨米人父母，这一比率仍然低于如果萨米人中MS患病率与其他挪威人相似时的预期值人口。研究表明，在Troms和Finnmark中，MS的发病率在过去10年中一直在增加，但仍低于西海岸和挪威东部。发生率最低的地区是芬马克省，萨米族人口最多。在过去的10年中，萨米族人还被诊断出MS。

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