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首页> 外文期刊>Journal of orthopaedic research >Estimation of dynamic, in vivo soft-tissue deformation: experimental technique and application in a canine model of tendon injury and repair.
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Estimation of dynamic, in vivo soft-tissue deformation: experimental technique and application in a canine model of tendon injury and repair.

机译：动态，体内软组织变形的估计：实验技术和在腱损伤和修复的犬模型中的应用。

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Outcomes after rotator cuff surgery are typically assessed with measures of strength, joint motion, or pain, but these measures do not provide a direct assessment of tissue function as healing progresses. To address this limitation, this manuscript describes biplane X-ray analysis as a technique for quantifying in vivo soft-tissue deformation. Tantalum beads were implanted in the humerus and infraspinatus tendon in a canine model of tendon injury and repair. Biplane X-ray images were acquired during treadmill trotting and tissue deformation was estimated from the three-dimensional bead positions. Changes over time were characterized by the mean, range, and normalized range (i.e., range/mean) of interbead distance. Intact tendon repair tissue demonstrated significant decreases over time in the mean (p = 0.003), range (p = 0.001), and normalized range (p = 0.001) of interbead distance. Failed tendon repair tissue demonstrated significant decreases over time in the range (p = 0.05) and normalized range (p = 0.04) of interbead distance. In an uninjured control, differences over time in the interbead distance parameters were not detected. This approach is a promising technique for estimating changes over time in soft-tissue deformation. These preliminary data indicate appreciable differences between normal tendons, intact repairs, and failed repairs.
机译：肩袖手术后的结果通常通过强度，关节运动或疼痛程度进行评估，但是这些措施不能随着愈合的进展直接评估组织功能。为了解决这一局限性，该手稿将双平面X射线分析描述为定量体内软组织变形的技术。在犬肌腱损伤和修复的模型中，将钽珠植入肱骨和鼻下肌腱。在跑步机小跑期间获取双翼X射线图像，并从三维磁珠位置估计组织变形。随时间变化的特征在于珠间距离的平均值，范围和标准化范围（即范围/平均值）。完整的腱修复组织显示珠间距离的平均值（p = 0.003），范围（p = 0.001）和归一化范围（p = 0.001）随时间显着降低。失败的腱修复组织在珠间距离范围内（p = 0.05）和归一化范围内（p = 0.04）随着时间的推移显着降低。在未损伤的对照中，未检测到珠间距离参数随时间的差异。该方法是用于估计软组织变形随时间变化的有前途的技术。这些初步数据表明正常肌腱，完整修复和修复失败之间存在明显差异。

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