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首页> 外文期刊>Journal of oral rehabilitation >In vivo evaluation of the biocompatibility of three current bonding agents.
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In vivo evaluation of the biocompatibility of three current bonding agents.

机译：体内评估三种当前结合剂的生物相容性。

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The aim of this in vivo study was to evaluate the biocompatibility of three current bonding agents and calcium hydroxide cement. Sixty polyethylene tubes filled with the following materials: Group 1: Prime & Bond NT (PB - Dentsply, US; Group 2: Bond 1 (BO - Jeneric/Pentron, US); Group 3: Optibond Solo (OP - Kerr, US); and Group 4 (control): calcium hydroxide cement - Dycal (CH - Dentsply, US) were implanted into the connective tissue of 30 rats. After 15, 30 and 60 days, the implants were excised and the animals sacrificed. The biopsies were immersed in Karnovsky (pH, 7.2) fixative solution for 48 hours, and processed using routine histological technique. Six-micron-thick sections were cut and stained with hematoxilin and eosin and Masson's trichome technique. Microscopic evaluation was used to compare the connective tissue reactions caused by the experimental and control materials adjacent to the tube opening. At 15 days, the experimental and control materials triggered a moderate to intense inflammatory response which gave rise to a thick capsule adjacent to the tube opening. With time, the inflammatory reaction decreased. At 60 days, the connective tissue adjacent to the bonding agents exhibited a persistent inflammatory response mediated by macrophages and giant cells which were engulfing displaced resin components. On the other hand, for the control group (calcium hydroxide) no inflammatory response associated with a thin capsule adjacent to the material was observed even at the 30-day period. The hard-setting calcium hydroxide cement allowed complete healing and was considered more biocompatible than the bonding agents.
机译：这项体内研究的目的是评估三种当前粘合剂和氢氧化钙水泥的生物相容性。 60根装有以下材料的聚乙烯管：第1组：Prime＆Bond NT（美国PB-Dentsply;第2组：Bond 1（BO-Jeneric / Pentron，美国）;第3组：Optibond Solo（OP-Kerr，美国） ;和第4组（对照组）：将氢氧化钙水泥-Dycal（CH-Dentsply，US）植入30只大鼠的结缔组织中，分别在15、30和60天后切除植入物并处死动物。将其浸入Karnovsky（pH，7.2）固定液中48小时，并使用常规组织学技术处理，将六微米厚的切片切成薄片，并用苏木精和曙红和Masson的毛状体技术染色，并用显微镜评估比较结缔组织反应在第15天，实验和对照材料触发了中度到强烈的炎症反应，并在导管开口附近形成了一个厚的囊膜。减少。在第60天，与结合剂相邻的结缔组织表现出持续的炎症反应，其由吞噬置换的树脂组分的巨噬细胞和巨细胞介导。另一方面，对于对照组（氢氧化钙），即使在30天的时期也没有观察到与邻近材料的薄胶囊相关的炎症反应。坚硬的氢氧化钙水泥可以完全愈合，并且被认为比粘合剂更具生物相容性。

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