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首页> 外文期刊>Journal of oral rehabilitation >Biofilm formation of Candida albicans on the surfaces of deteriorated soft denture lining materials caused by denture cleansers in vitro.
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Biofilm formation of Candida albicans on the surfaces of deteriorated soft denture lining materials caused by denture cleansers in vitro.

机译：假牙清洁剂在体外导致变质的假牙衬里材料表面上白色念珠菌的生物膜形成。

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Candidal colonization and subsequent biofilm formation on denture materials are important in the development of pathogenesis, such as denture stomatitis. Routine use of denture cleansers is one of the most effective methods of denture plaque control, although the incompatibility of soft liners and denture cleansers cause damage to the materials. The present study, biofilm formation of Candida albicans on the surfaces of soft denture lining materials, immersed in denture cleansers for 180 days were studied. Seven commercially available soft denture lining materials, were artificially deteriorated by immersion into three commercially available denture cleansers for 180 days, and subsequent fungal growth and biofilm formation were studied by measuring pH of the media and by the use of adenosine triphosphate (ATP) analysis. Fungal biofilm formation on the deteriorated soft liners varied depending upon the combination of the soft liners and denture cleansers. Several combinations of soft liners with denturecleansers exhibited the significantly high colonization capacity as compared with each sample immersed in distilled water, used as individual controls. The relationship between the biofilm formation on the samples of each material and the surface roughness of the soft lining materials was analyzed. However, no significant correlation was observed. The results, taken together, suggested that fungal colonization could be predominantly regulated by the combination of lining material with denture cleansers. In clinical terms, our findings suggests that daily cleansing of soft lining materials with mismatched denture cleansers promoted the subsequent biofilm formation of fungi on the materials.
机译：假牙材料上的念珠菌定植和随后的生物膜形成在诸如假牙口炎的发病机理发展中很重要。常规使用义齿清洁剂是控制义齿斑块的最有效方法之一，尽管软衬板和义齿清洁剂的不兼容会损坏材料。本研究研究了假牙衬里材料在假牙清洁剂中浸泡180天后在假牙衬里材料表面形成白色念珠菌的生物膜。七种可商购的软义齿衬里材料通过浸入三个可商购的义齿清洁剂中180天而被人工降解，随后通过测量培养基的pH值和使用三磷酸腺苷（ATP）分析研究了真菌的生长和生物膜的形成。劣化的软衬里上的真菌生物膜形成取决于软衬里和义齿清洁剂的组合而变化。与浸入蒸馏水中的每个样品（用作单独的对照）相比，软衬板与假牙清洁剂的几种组合具有明显高的定殖能力。分析了每种材料样品上生物膜的形成与软衬材料表面粗糙度之间的关系。但是，没有观察到明显的相关性。综上所述，结果表明，真菌的定居可以主要通过衬里材料与义齿清洁剂的结合来调节。在临床上，我们的发现表明，每天使用不匹配的义齿清洁剂清洁软衬材料会促进随后在材料上形成真菌的生物膜。

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