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Triggering psoriasis: the role of infections and medications.

机译:触发牛皮癣:感染和药物的作用。

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Psoriasis can be provoked or exacerbated by a variety of different environmental factors, particularly infections and drugs. Strong evidence exists for the induction of guttate psoriasis by a preceding tonsillar Streptococcus pyogenes infection, whereas disease exacerbation has been linked with skin and/or gut colonization by Staphylococcus aureus, Malassezia, and Candida albicans. The role, if any, of viruses (papillomaviruses, HIV, and endogenous retroviruses) present in lesional skin is at present unknown. The use of various drugs, such as lithium, beta-blockers, antimalarial agents, nonsteroidal anti-inflammatory drugs, and angiotensin-converting enzyme inhibitors, has also been associated with induction or worsening of disease in psoriatic patients.
机译:各种不同的环境因素,尤其是感染和药物,可能引起或加剧牛皮癣。有强有力的证据表明先前的扁桃体扁桃链球菌感染可诱发肠状牛皮癣,而金黄色葡萄球菌,马拉色氏菌和白色念珠菌的病情恶化与皮肤和/或肠道定植有关。目前尚不清楚病灶皮肤中病毒(乳头瘤病毒,HIV和内源性逆转录病毒)的作用(如果有的话)。各种药物的使用,例如锂,β-阻滞剂,抗疟药,非甾体抗炎药和血管紧张素转化酶抑制剂,也与银屑病患者的疾病诱发或恶化有关。

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