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The Etiology and Natural History of Idiopathic Scoliosis

机译:特发性脊柱侧弯的病因和自然史

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Idiopathic scoliosis (IS) can be defined as a lateral curvature of the spine, greater than 10?as measured by the Cobb method,1 in the absence of any relevant congenital spinal anomalies or associated musculoskeletal conditions. The true etiology of IS remains unknown, but its cause is thought to be multifactorial. The intent of this article is primarily threefold: 1) To summarize the etiological factors thought to be associated with IS, consistent with an outline recently published by the Scoliosis Research Society's (SRS) Etiology Committee2; 2) To summarize what is currently understood about the natural history of IS, identifying various "risk factors" for possible curve progression, and 3) To identify the general thinking about when orthotic management is indicated, and summarize the evidence of its ability to alter the natural history of the disease.
机译:特发性脊柱侧弯(IS)可以定义为脊柱的侧向弯曲,在没有任何相关的先天性脊柱异常或相关的肌肉骨骼疾病的情况下,通过Cobb方法测量1,大于10?。 IS的真正病因仍然未知,但其原因被认为是多因素的。本文的目的主要是三方面的:1)总结被认为与IS相关的病因,与脊柱侧凸研究协会(SRS)病因学委员会最近发表的大纲相一致2。 2)总结当前对IS的自然病史的理解,确定可能的曲线发展的各种“风险因素”,以及3)识别何时需要矫正治疗的一般思路,并总结其改变能力的证据疾病的自然病史。

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