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Disparities in the severity of influenza illness: A descriptive study of hospitalized and nonhospitalized novel H1N1 influenza-positive patients in New York city: 2009-2010 influenza season

机译:流感疾病严重程度差异:纽约市住院和非住院新型H1N1流感阳性患者的描述性研究:2009-2010流感季节

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Objective: To investigate the association between socioeconomic status (SES) and hospitalization for 2009 H1N1 influenza, independently of access to care and known risk factors for severe influenza illness, among New York City residents during the 2009-2010 influenza season. Design: We used a 1:2 case-control study design, matching by age group and month of diagnosis. Cases were defined as laboratory-confirmed patients with 2009 H1N1 influenza who were hospitalized during their illness. Controls were defined as nonhospitalized laboratory-confirmed influenza A patients. Participants were contacted for a telephone interview to collect relevant clinical and demographic data. We used conditional logistic regression to analyze the association between SES and hospitalization. Setting: New York City. Participants: Of the 171 hospitalized cases who were identified between October 2009 and February 2010, a total of 128 completed telephone interviews. A total of 640 nonhospitalized controls were contacted, and of these, 337 completed interviews. Main Outcome Measures: The main outcome of interest was whether or not a patient was hospitalized during his or her 2009 H1N1 influenza illness. Socioeconomic status was measured using education and neighborhood poverty. Results: We identified a gradient in the odds of hospitalization for 2009 H1N1 influenza by education level among adults. This association could not be entirely explained by access to care and underlying risk factors. An inverse association between odds of hospitalization and neighborhood poverty was also identified among adults and children. Conclusions: This study suggests that individuals of lower SES were more vulnerable to severe illness during the 2009 H1N1 pandemic. Additional research is needed to help guide interventions to protect this population during future influenza pandemics.
机译:目的:调查2009-2010年流感季节期间纽约市居民的2009年H1N1流感社会经济状况(SES)与住院之间的关系,与获得护理和严重流感疾病的已知危险因素无关,不依赖于获得治疗的机会。设计:我们使用了1:2的病例对照研究设计,并根据年龄组和诊断月份进行了匹配。病例定义为经过实验室确诊的2009年H1N1流感患者,他们在患病期间住院。对照定义为未经医院确认的甲型流感患者。与参与者进行了电话访谈,以收集相关的临床和人口统计学数据。我们使用条件逻辑回归分析了SES与住院之间的关联。地点:纽约市。参加者:在2009年10月至2010年2月期间确定的171例住院病例中,共有128例完成了电话采访。总共联系了640名非住院对照者,其中337名完成了访谈。主要结局指标:感兴趣的主要结局是患者在其2009年H1N1流感疾病期间是否住院。社会经济地位是通过教育和社区贫困来衡量的。结果:我们根据成人的教育水平,确定了2009年H1N1流感住院率的梯度。不能通过获得护理和潜在风险因素来完全解释这种关联。在成年人和儿童中,住院几率与社区贫困之间也存在负相关关系。结论:这项研究表明,在2009年H1N1大流行期间,具有较低SES的个体更容易受到严重疾病的侵害。需要进行进一步的研究以帮助指导干预措施,以在未来的流感大流行中保护这一人群。

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