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首页> 外文期刊>Journal of Reproductive Immunology >Limited uptake of foreign materials by resident macrophages in murine ovarian tissues.
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Limited uptake of foreign materials by resident macrophages in murine ovarian tissues.

机译：鼠卵巢组织中常驻巨噬细胞对异物的吸收有限。

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摘要

In the present study, the distributions of exogenously administered horseradish peroxidase (HRP) and colloidal carbon in gonadal tissues were observed in both male and female mice using light microscopy. HRP was injected intravenously and colloidal carbon was directly injected into the gonadal parenchyma. Thereafter, the gonads were obtained for histological examination. The results showed that staining of HRP and carbon was detected in the ovaries at a low level. In contrast, much staining was observed in the interstitial cells of the testes for a long period. This suggests that ovarian tissues are less active in the uptake of exogenous materials than testicular tissues in vivo. However, immunohistochemical examination using anti-macrophage antibodies revealed that the ovaries contained a large number of macrophages, as did the testes, under normal conditions. Therefore, the results indicate that resident macrophages in the ovaries exhibit weak endocytic activity of foreign materials in vivo.
机译：在本研究中，使用光学显微镜在雄性和雌性小鼠中观察到外源施用的辣根过氧化物酶（HRP）和胶体碳在性腺组织中的分布。静脉注射HRP，将胶体碳直接注射到性腺实质中。此后，获得性腺用于组织学检查。结果显示在卵巢中检测到HRP和碳的染色低。相反，长期在睾丸的间质细胞中观察到很多染色。这表明卵巢组织在体内吸收外源性物质方面不如体内睾丸组织活跃。然而，使用抗巨噬细胞抗体的免疫组织化学检查显示，在正常条件下，卵巢和睾丸一样含有大量巨噬细胞。因此，该结果表明卵巢中的常驻巨噬细胞在体内表现出弱的内源性吞噬活性。

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