...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Reproductive Medicine: The Official Periodical of the American Academy of Reproductive Medicine, Association of Professors of Gynecology and Obstetrics, International Family Planning Research Association ... [et al.] >Menopausal vasomotor symptoms: a review of causes, effects and evidence-based treatment options.
【24h】

Menopausal vasomotor symptoms: a review of causes, effects and evidence-based treatment options.

机译：更年期血管舒缩症状：原因，影响和循证治疗选择的回顾。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Vasomotor symptoms are the most common medical complaint of perimenopausal and postmenopausal women. Frequent vasomotor symptoms can be disabling, affecting a woman's social life, psychological health, sense of well-being and ability to work. Women with hot flushes are more likely to experience disturbed sleep, depressive symptoms and significant reductions in quality of life as compared to asymptomatic women. Despite the prevalence and impact of these symptoms, the pathophysiology of hot flushes is unclear; however, estrogen withdrawal clearly plays an important role. It is postulated that declining estrogen concentrations may lead to changes in brain neurotransmitters and instability in the hypothalamic thermoregulatory center. The most effective therapy for relieving vasomotor symptoms and reducing their impact on quality of life is hormone therapy. Other options for women who decline hormone therapy include selective serotonin reuptake inhibitors and related agents. Most herbal therapies that have been evaluated in placebo-controlled trials have shown no clinically significant benefit.
机译：血管舒缩症状是绝经后和绝经后妇女最常见的医学主诉。频繁的血管舒缩症状可能会致残，从而影响女性的社交生活，心理健康，幸福感和工作能力。与无症状的女性相比，潮热的女性更容易出现睡眠障碍，抑郁症状和生活质量显着下降。尽管这些症状普遍存在并受到影响，但潮热的病理生理机制尚不清楚。然而，雌激素戒断显然起着重要作用。据推测，雌激素浓度的下降可能导致脑神经递质的变化和下丘脑温度调节中心的不稳定。缓解血管舒缩症状并减少其对生活质量影响的最有效疗法是激素疗法。拒绝接受激素治疗的女性的其他选择包括5-羟色胺再摄取抑制剂和相关药物。在安慰剂对照试验中评估过的大多数草药疗法均未显示出临床显着的获益。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号