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首页> 外文会议>Symposium on Risk Assessment of Phytochemicals in Food: Novel Approaches >Risk-Benefit Considerations of Isoflavone Supplements in the Treatment of Menopausal Vasomotor Symptoms
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Risk-Benefit Considerations of Isoflavone Supplements in the Treatment of Menopausal Vasomotor Symptoms

机译：异黄酮补充剂的风险效益考虑因素血管运动症症状的治疗

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摘要

Isoflavones are oestrogen-like substances that occur in large amounts in soy-beans. These phytochemicals bind to oestrogen receptors and exert various oes-trogenic or anti-oestrogenic effects. Soybeans contain three primary isoflavones in their glycoside form: genistin, daidzin and glycitin. Because consumption of these compounds has been associated with several health benefits, they are be-coming increasingly popular as food supplements and are frequently advertised as a natural and safe alternative to menopausal hormone therapy. Currently, numerous isoflavone preparations derived from soy are available on the mar-ket and are used by many women to relieve their menopausal hot flushes and night sweats. These supplements are hardly comparable because of variations in isoflavone source, manufacturing process, the inadequate information on composition and major deviations between the declared contents and actual composition, as well as varying consumption recommendations, complicating the assessment of their risk and efficacy in humans.
机译：异黄酮是雌激素样物质，大量在大豆中发生。这些植物化学物质与雌激素受体结合并施加各种OES-衰老或抗雌激素的作用。大豆含有糖苷形式的三种主要异黄酮：甘氨酸，Daidzin和糖糖苷。由于这些化合物的消耗与多种健康益处有关，因此它们越来越受到食物补充剂，并且经常被广告为更年期激素治疗的自然和安全的替代品。目前，衍生自大豆的许多异黄酮制剂可在Mar-Ket上获得，并且许多女性使用，以缓解它们的更年期热冲洗和盗汗。由于异黄酮源，制造过程的变化，这些补充剂几乎不可媲美，制造过程不足以及宣布的内容和实际组成之间的构成和主要偏差，以及不同的消费建议，使对人类风险和疗效的评估复杂化。

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