• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical and experimental obstetrics and gynecology >Phytoestrogens for menopausal vasomotor symptoms: efficacy of soybean isoflavones supplements for alleviating menopausal symptoms is positively related to hot flushes frequency
【24h】

Phytoestrogens for menopausal vasomotor symptoms: efficacy of soybean isoflavones supplements for alleviating menopausal symptoms is positively related to hot flushes frequency

机译：植物雌激素症状：大豆异黄酮的疗效减轻更年期症状的补充剂与热冲洗频率呈正相关

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose of investigation: This study was designed to measure the beneficial effects of a combination of nutraceutics containing soy isoflavones (80 mg) and to evaluate the effect of soy isoflavones on hot flushes (HP) and quality of life in a clinical setting, as the authors conducted an observational study. Materials and Methods: This study was conducted on 92 patients with complaints of hot flashes, divided into two groups of 46 each. Group 1 received no therapy and group 2 received 80 mg of isoflavones daily for six months. The patients were interviewed to calculate hot flashes, global and depression scores and were rescored after 2, 4, 8, 12 and 24 weeks. The primary outcome measure was a change in the HF score from baseline. Results: A total of 92 patients, 46 (50%) in the treated group and 46 (50%) in the untreated group, entered the study. Extracts containing high levels of genistein (a substance derived from soy) appeared to reduce the number of daily HF and need to be investigated further. No indication suggested that discrepant results were due to the amount of isoflavones in the active treatment arm, the severity of vasomotor symptoms or trial quality factors. Also, no evidence indicated that these treatments caused oestrogenic stimulation of the endometrium or of the vagina or other adverse effects when used for up to one year. Conclusions: This observational trial suggests a possible beneficial effect of a dietary soy supplement containing 80 mg of isoflavones/day in the management of menopausal symptoms such as HF.
机译：调查目的：本研究旨在衡量含有大豆异黄酮（80mg）的营养素组合的有益效果，并评估大豆异黄酮对热冲洗（HP）和临床环境中的生活质量的影响，为作者进行了一个观察性研究。材料和方法：本研究于92名热闪光患者进行，分为两组46。第1组未接受治疗，第2组每天收到80毫克异黄酮六个月。接受采访患者计算热闪烁，全球和抑郁分数，并在2,4,8,12和24周后进行恢复。主要结果措施是基线的HF评分的变化。结果：治疗组共有92名患者，46名（50％），未经处理的组中46（50％）进入该研究。含有高含量的结脂（来自大豆的物质）的提取物似乎减少了每日HF的数量，并且需要进一步研究。没有指示表明差异结果是由于活性治疗臂中异黄酮的量，血管运动症状或试验质量因素的严重程度。此外，没有证据表明这些治疗导致在使用最多一年时造成的雌激素刺激子宫内膜或阴道或其他不良反应。结论：这种观察力试验表明，含有80毫克异黄酮/日的膳食大豆补充剂的可能有益效果在诸如HF等绝经症状的管理中。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号