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首页> 外文期刊>Journal of refractive surgery >Treating keratoconus with intacs corneal ring segments.
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Treating keratoconus with intacs corneal ring segments.

机译：用intacs角膜环段治疗圆锥角膜。

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摘要

PURPOSE: To assess the safety and efficacy of Intacs inserts for the treatment of mild to moderate keratoconus. METHODS: In a nonrandomized prospective clinical trial, 50 eyes of 37 patients with mild to moderate keratoconus were implanted with asymmetrical pairs of Intacs segments. Patients were interviewed and observed preoperatively and 24 hours, 1 week, 1, 3, 6, and 12 months postoperatively. Main outcome measures were uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refraction, satisfaction with vision and trouble with vision, Visual Function-7 score, and surgically induced change in corneal astigmatism. RESULTS: Of the 50 operations performed, 92% were successful. Mean follow-up was 6.3 +/- 3.2 months. In 4 (8%) eyes, both Intacs segments were removed. In addition, 7 refractive adjustments in 7 eyes were performed successfully to improve visual and surgical outcome. Both BSCVA and UCVA improved throughout follow-up. Visual functioning index improved from 61.6 +/- 21.1 to 80.8 +/- 22.5, and the percentage of satisfaction with vision improved from 24.3% to 87.5% at 12 months. Vector analysis of astigmatism correction showed that the mean change in corneal astigmatism was 2.9 +/- 2.9 D at 6 months postoperatively. By selecting patients in whom astigmatism correction was best (index of success >0.5), an analysis was performed to determine individual factors important in successful surgery. Preoperatively these 11 (22%) eyes did not differ significantly from the remaining eyes and the only significant value was low K readings in the flat axis. CONCLUSIONS: Asymmetric Intacs placement improves BSCVA and UCVA and reduces astigmatism in patients with mild to moderate keratoconus. The procedure of Intacs placement is safe and effective. The change in astigmatism correction is unpredictable.
机译：目的：评估Intacs插件治疗轻度至中度圆锥角膜的安全性和有效性。方法：在一项非随机的前瞻性临床试验中，对37例轻度至中度圆锥角膜患者的50只眼植入了不对称的Intacs段对。术前以及术后24小时，1周，1、3、6和12个月对患者进行了访谈和观察。主要结局指标为未矫正视力（UCVA），最佳眼镜矫正视力（BSCVA），验光，对视力的满意度和视力障碍，Visual Function-7评分以及手术引起的角膜散光的变化。结果：在执行的50项手术中，有92％成功。平均随访时间为6.3 +/- 3.2个月。在4（8％）眼中，两个Intacs段均被切除。此外，成功进行了7只眼的7次屈光调节，以改善视觉和手术效果。在整个随访过程中，BSCVA和UCVA均得到改善。视觉功能指数从61.6 +/- 21.1提高到80.8 +/- 22.5，在12个月时对视觉的满意率从24.3％提高到87.5％。散光矫正的载体分析表明，术后6个月角膜散光的平均变化为2.9 +/- 2.9D。通过选择散光矫正效果最好的患者（成功指数> 0.5），进行分析以确定对成功手术重要的个体因素。术前这11只眼（22％）与其余的眼睛没有显着差异，唯一的重要意义是平轴上的K值低。结论：不对称的Intacs放置可改善轻度至中度圆锥角膜患者的BSCVA和UCVA并减少散光。 Intacs放置的过程是安全有效的。散光校正的变化是不可预测的。

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