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首页> 外文期刊>Journal of refractive surgery >Experimental model of laser in situ keratomileusis in hens.
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Experimental model of laser in situ keratomileusis in hens.

机译：母鸡激光原位角膜磨镶术的实验模型。

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PURPOSE: To develop an experimental animal model of laser in situ keratomileusis (LASIK) in hens. METHODS: One hundred adult hens underwent a 60-microm corneal flap followed by -4 diopter excimer laser ablation. Surgical technique, clinical course, and pathology correlations are presented. RESULTS: Sixty percent of animals had a successful LASIK outcome according to clinical observations. Pathology showed the integrity of Bowman's layer and homogeneous flap in all eyes with good clinical outcomes. Flap complications such as buttonholes (5%), free-flaps (2%), and slipped flaps (3.4%) occurred with the surgical technique. Corneal abscess (2.9%) was also present. Loss of transparency was noted in 26.4%, which correlates with epithelial ingrowth detected by light histology study. CONCLUSIONS: An experimental animal model of LASIK was successfully developed in adult hens. This model could be useful in the study of wound healing and pharmacological modulation after LASIK in an animal with Bowman's layer.
机译：目的：建立母鸡激光原位角膜磨镶术（LASIK）的实验动物模型。方法：对一百只成年母鸡进行60微米的角膜瓣，然后用-4屈光度准分子激光消融。介绍了手术技术，临床过程和病理学相关性。结果：根据临床观察，有60％的动物获得了成功的LASIK结果。病理显示所有眼睛的鲍曼层和均匀皮瓣完整，临床效果良好。瓣膜并发症包括锁眼（5％），皮瓣（2％）和皮瓣打滑（3.4％）。还存在角膜脓肿（2.9％）。注意到透明性损失为26.4％，这与通过光组织学研究检测到的上皮向内生长相关。结论：成年母鸡成功建立了LASIK实验动物模型。该模型可用于研究具有Bowman's层的动物中LASIK术后的伤口愈合和药理调节。

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