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首页> 外文期刊>Journal of Parasitology >Contribution of NADH dehydrogenase subunit I and cytochrome C oxidase subunit I sequences toward identifying a case of human coenuriasis in France.
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Contribution of NADH dehydrogenase subunit I and cytochrome C oxidase subunit I sequences toward identifying a case of human coenuriasis in France.

机译:在法国,NADH脱氢酶亚基I和细胞色素C氧化酶亚基I序列对鉴定人类遗尿症的贡献。

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摘要

Coenuriasis is a parasitic disease induced by larval taeniid tapeworms that is rarely observed in humans. In December 2005, a case was diagnosed in Nancy, France, after surgical excision of a cyst on a 24-yr-old woman returning from the Cote d'Ivoire. Morphological and epidemiological criteria suggested that the infection was due to Taenia serialis. Molecular analysis of NADH dehydrogenase subunit I (NDI) and cytochrome c oxidase subunit I (COI) sequences was also in favor of T. serialis identification, but the absence of available genetic data on T. brauni and T. glomeratus and the small number of published sequences for T. serialis and T. multiceps must be considered with caution. The NDI partial sequences presented more variations within species of Taenia than the COI sequences, which make them more useful targets for species identification and analysis of intraspecific polymorphisms. The present study points to the usefulness of molecular biology tools to help make up for the shortcomings of the commonplace parasitological diagnosis for coenuriasis.
机译:enenuriasis是由幼虫taeniid worm虫引起的寄生虫病,在人类中很少观察到。 2005年12月,在法国南锡,一名外科手术切除了一名从科特迪瓦返回的24岁妇女的囊肿后,诊断出一个病例。形态学和流行病学标准表明,感染是由于连续带Ta虫引起的。 NADH脱氢酶亚基I(NDI)和细胞色素C氧化酶亚基I(COI)序列的分子分析也有利于序列衣原体的鉴定,但是缺乏有关布朗氏衣原体和肾小球体的现有遗传数据,并且缺乏必须谨慎考虑已发表的序列虫和多囊菌的序列。与COI序列相比,NDI部分序列在Ta虫种内表现出更多的变异,这使它们成为物种鉴定和种内多态性分析的更有用靶标。本研究指出分子生物学工具的有用性,以帮助弥补常见的寄生虫病寄生虫学诊断的缺点。

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