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首页> 外文期刊>Journal of Parasitology >Blastocystis spp.: frequency and subtype distribution in iron deficiency anemic versus non-anemic subjects from Egypt.
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Blastocystis spp.: frequency and subtype distribution in iron deficiency anemic versus non-anemic subjects from Egypt.

机译：Blastocystis spp .：来自埃及的缺铁性贫血与非贫血受试者的频率和亚型分布。

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摘要

Many helminthic and protozoal infections have been implicated in iron deficiency anemia (IDA) but few reports have suggested a link between Blastocystis sp. infection and IDA. Herein, we investigated the frequency and the association of the Blastocystis sp. genotype with IDA. Two-hundred and six stool samples were examined for Blastocystis sp. Samples were obtained from 96 cases with a confirmed diagnosis of IDA and 110 matched non-anemic controls. The prevalence of the parasite was significantly higher in the IDA group (54.2%) when compared to controls (17.3%) and was 34.5% in all study subjects. Thus, a relationship between Blastocystis sp. infection and IDA was confirmed. PCR amplification of isolates from cases with IDA and controls using subtype-specific sequenced-tagged site primers found that subtype 3 was the most common (83.3%), followed by subtype 1 (16.7%), and both had similar prevalence in both groups. Therefore, there was no correlation found between the Blastocystis sp. genotype and the occurrence of IDA.
机译：许多蠕虫和原生动物感染都与缺铁性贫血（IDA）有关，但很少有报道表明Blastocystis sp。之间存在联系。感染和IDA。在这里，我们调查了频率和Blastocystis sp的关联。 IDA的基因型。检查了200个和6个粪便样本中的Blastocystis sp。从确诊为IDA的96例患者和110例匹配的非贫血对照组中获取样本。与对照组（17.3％）相比，IDA组中的寄生虫患病率（54.2％）显着更高，在所有研究对象中均为34.5％。因此，Blastocystis sp。感染和IDA被确认。使用亚型特异性测序标签位点引物对IDA病例和对照的分离株进行PCR扩增发现，亚型3最常见（83.3％），其次是亚型1（16.7％），两组患病率相似。因此，在Blastocystis sp。之间没有发现相关性。基因型和IDA的发生。

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