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首页> 外文期刊>Journal of separation science. >Two-dimensional liquid chromatography and its application in traditional Chinese medicine analysis and metabonomic investigation
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Two-dimensional liquid chromatography and its application in traditional Chinese medicine analysis and metabonomic investigation

机译：二维液相色谱法及其在中药分析和代谢组学研究中的应用

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摘要

Two-dimensional liquid chromatography has become an attractive analytical tool for the separation of complex samples due to its enhanced selectivity, peak capacity, and resolution compared with one-dimensional liquid chromatography. Recently, more attention has been drawn on the application of this separation technique in studies concerning traditional Chinese medicines, metabonomes, proteomes, and other complex mixtures. In this review, we aim to examine the application of two-dimensional liquid chromatography in traditional Chinese medicine analysis and metabonomic investigation. The classification and evaluation indexes were first introduced. Then, various switching methods were summarized when used in an on-line two-dimensional liquid chromatography system. Finally, the applications of this separation technique in traditional Chinese medicine analysis and metabonomic investigation were discussed on the basis of specific studies.
机译：由于与一维液相色谱相比，二维液相色谱具有更高的选择性，峰容量和分离度，它已成为用于分离复杂样品的有吸引力的分析工具。近来，这种分离技术在有关中药，代谢组学，蛋白质组学和其他复杂混合物的研究中的应用引起了更多关注。在这篇综述中，我们旨在研究二维液相色谱在中药分析和代谢组学研究中的应用。首先介绍了分类和评估指标。然后，总结了在在线二维液相色谱系统中使用时的各种切换方法。最后，在具体研究的基础上，讨论了该分离技术在中药分析和代谢组学研究中的应用。

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