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Chromatographic fingerprinting and related chemometric techniques for quality control of traditional Chinese medicines

机译:色谱指纹图谱及相关化学计量技术在中药质量控制中的作用

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摘要

Development of chromatographic fingerprint (CF) and related chemometric methods and their applications to quality control of traditional Chinese medicines (TCMs) were discussed CF is essentially a kind of quality control method for TCMs (or Chinese herbal medicines). Also, it is a quality-relevant-data high-throughput and integral tool to explore chemically the complexity of TCMs. With the help of chemometrics, some difficulties in evaluation and analysis of CFs, such as calculation of information content, peak alignment. pattern analysis, deconvolution of overlapping peaks, etc. could be well solved To further explore TCMs synergic quality, intensive study of CF coupled with chemometrics will create the possibility to achieve the aim to reveal the working mechanisms of TCMs and to further control and strengthen TCMs' intrinsic quality in a comprehensive manner.
机译:讨论了色谱指纹图谱(CF)的发展以及相关的化学计量学方法及其在中药(TCMs)质量控制中的应用。CF本质上是一种中药(或中草药)的质量控制方法。同样,它是一种质量相关数据高通量且不可或缺的工具,可以从化学角度探索中药的复杂性。借助化学计量学,评估和分析CF时会遇到一些困难,例如信息含量的计算,峰比对。模式分析,重叠峰解卷积等可以很好地解决。为了进一步探索中药的协同质量,对CF进行深入研究并结合化学计量学将为实现揭示中药的工作机制以及进一步控制和加强中药提供可能。内在素质全面提升。

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