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首页> 外文期刊>Cochlear implants international >Paediatric cochlear implantation: Adverse prognostic factors and trends from a review of 174 cases
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Paediatric cochlear implantation: Adverse prognostic factors and trends from a review of 174 cases

机译：小儿人工耳蜗植入：174例患者的不良预后因素和趋势

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Objectives: Identification and evaluation of prognostic factors that are associated with paediatric cochlear implantation (PCI) outcomes was the aim of this study. Methods: A retrospective review of 174 charts was performed at the Royal Children's Hospital and the Hear and Say Centre, Brisbane. This examined the possible influence of a number of variables (including age at implant, family, additional disabilities, surgical complications, gender, GJB2 mutations, meningitis, inner ear malformations, and prematurity) on outcome measures: receptive, expressive, and total language, receptive and expressive vocabulary, speech articulation and categories of auditory performance at 18-24 months post-implant. Multiple regression analysis was used to identify variables related to language and vocabulary outcomes. Results: The findings suggest that inner ear malformations and family concern are negatively associated with receptive and expressive language and receptive vocabulary scores. There was marginal evidence to suggest that increasing age at implantation was associated with lower receptive and expressive language scores. Discussion: Prognostic factors that have been adequately validated statistically include inner ear malformations, the influence of family and late age at implantation. However, this study identified a need to define better the impact of the various degrees of inner ear malformations, to particularly emphasize the role of family as a strong predictor of PCI outcomes, and to confine the study of 'age at implantation' to pre-lingually deafened children. Conclusion: Evaluation of prognostic factors is a key element in PCI. This study confirmed several factors that are strongly associated with outcomes. For better research, there is a need for universal standardized outcome measures and development of a standardized framework for recording patient data.
机译：目的：鉴定和评估与小儿人工耳蜗植入（PCI）结果相关的预后因素是本研究的目的。方法：在皇家儿童医院和布里斯班听与说中心进行了174张图表的回顾性回顾。本研究考察了以下变量对结果指标的可能影响（包括植入物的年龄，家庭，额外的残疾，外科手术并发症，性别，GJB2突变，脑膜炎，内耳畸形和早产），这些指标包括：接受，表达和总语言，植入后18-24个月的接受性和表达性词汇，语音清晰度和听觉表现类别。多元回归分析用于识别与语言和词汇结果相关的变量。结果：研究结果表明，内耳畸形和家庭关系与接受和表达语言以及接受词汇得分负相关。有少量证据表明植入时年龄的增长与较低的接受和表达语言得分有关。讨论：经统计学充分验证的预后因素包括内耳畸形，家庭的影响和植入时的年龄晚。但是，这项研究发现有必要更好地定义各种程度的内耳畸形的影响，尤其要强调家庭作为PCI预后的有力预测指标的作用，并将“植入年龄”的研究局限于耳聋的儿童。结论：预后因素的评估是PCI的关键要素。这项研究证实了与结局密切相关的几个因素。为了更好的研究，需要通用的标准化结果测量和开发用于记录患者数据的标准化框架。

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