A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling

Tsang Siu Wai; Ip Siu Po; Wu Justin Che-Yuen; Ng Siew-Chien; Yung Ken Kin-Lam; Bian Zhao-Xiang

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A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling

机译：一种中药制剂，通过抑制核因子-κB信号转导的活性来改善硫酸葡聚糖钠诱导的实验性结肠炎

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Ethnopharmacological relevance: Inflammatory bowel disease (IBD) is generally associated with a set of debilitating symptoms including abdominal pain, tenesmus, diarrhea and bloody stool. The standard approaches for treating IBD, which are the application of pharmaceuticals, are often unsatisfactory. IBD patients may suffer from repeated relapses and even exacerbation after taking these medications. Thus, patients are increasingly seeking relief through the use of complementary and alternative medicines.

机译：民族药理学意义：炎症性肠病（IBD）通常与一系列令人衰弱的症状有关，包括腹痛，里急后重，腹泻和便血。用于治疗IBD的标准方法，即药物的应用，通常不能令人满意。服用这些药物后，IBD患者可能会反复复发甚至加重病情。因此，患者越来越多地通过使用补充和替代药物寻求缓解。

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来源
《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs》 |2015年第null期|共11页
作者
Tsang Siu Wai; Ip Siu Po; Wu Justin Che-Yuen; Ng Siew-Chien; Yung Ken Kin-Lam; Bian Zhao-Xiang;
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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Inflammatory bowel disease (IBD); Ulcerative colitis (UC); Diarrhea; Bloody stool; Dextran sulfate sodium (DSS); Nuclear factor-kappaB (NF-kappa B);

机译：炎症性肠病（IBD）;溃疡性结肠炎（UC）;腹泻;血便;粪便中的右旋糖酐硫酸钠（DSS）;核因子-κB（NF-κB）;

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1. A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling [J] . Tsang Siu Wai, Ip Siu Po, Wu Justin Che-Yuen, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2015,第Null期

机译：一种中药制剂，通过抑制核因子-κB信号转导的活性来改善硫酸葡聚糖钠诱导的实验性结肠炎
2. Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation [J] . Liu Xiuting, Zhou Wei, Zhang Xin, Biochemical Pharmacology . 2016,第Null期

机译：富马酸二甲酯通过激活Nrf2和抑制NLRP3炎性体激活来改善硫酸葡聚糖钠诱导的鼠实验性结肠炎
3. Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation [J] . Guo Wenjie, Liu Wen, Jin Biao, International immunopharmacology . 2015,第2期

机译：亚洲酸改善硫酸葡聚糖钠诱导的小鼠实验性结肠炎通过抑制线粒体介导的NLRP3炎性组活化
4. Suppressive activity of a fermented grain food product on dextran sulfate sodium-induced experimental colitis in mice [C] . Ki Han Kwon, Akira Murakami, Takuji Tanaka, International Conference on Food Factors . 2004

机译：抑制发酵谷物食品对小鼠葡聚糖钠钠诱导的实验性结肠炎的抑制活性
5. Role of Osteopontin During Dextran Sulfate Sodium-induced Colitis. [D] . Paes Batista da Silva, Andre. 2009

机译：骨桥蛋白在硫酸葡聚糖钠诱导的结肠炎中的作用。
6. Brusatol-Enriched Brucea javanica Oil Ameliorated Dextran Sulfate Sodium-Induced Colitis in Mice: Involvement of NF-κB and RhoA/ROCK Signaling Pathways [O] . Xinghan Zheng, Liting Mai, Tongtong Wang, 2021

机译：Brusatol-Rucea javanica油改善葡聚糖硫酸钠诱导的小鼠的结肠炎：NF-κB和rhOO /岩石信号通路的累积
7. Oxyresveratrol Ameliorates Dextran Sulfate Sodium-Induced Colitis in Rats by Suppressing Inflammation [O] . Jiah Yeom, Seongho Ma, Jeong-Keun Kim, 2021

机译：通过抑制炎症，oxyresvertrol改善大鼠硫酸葡聚糖钠诱导的结肠炎

A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling

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